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zhangf's profile
Feng Zhang
Feng Zhang
Feng Zhang
@zhangf

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Feng Zhang

@zhangf

Researcher at Broad Institute and McGovern Institute at MIT.

Cambridge, MA
zhanglab.bio
Joined April 2015

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    Feng Zhang‏ @zhangf 5 May 2020

    We are excited to share STOPCovid, an inexpensive, one-step, & sensitive #COVID-19 detection protocol developed with @omarabudayyeh & @jgooten. This revamped assay was streamlined with the future goal of developing an in-home test for COVID-19. https://zlab.bio/s/COVID-19-detection-v.20200505 … 1/Xpic.twitter.com/ZxM7GrEvBc

    8:20 AM - 5 May 2020
    • 1,354 Retweets
    • 3,102 Likes
    • Cheryl Edwards Pradyumna Mulpur Carlo Thissen 📌 Manuela Casasoli Yingying Luis M. Ruiz Gregory H. James Sr. Kiera Howarth Adrian Bebenek
    40 replies 1,354 retweets 3,102 likes
      1. New conversation
      2. Feng Zhang‏ @zhangf 5 May 2020

        #STOPCovid requires no sample extraction, can be performed using a single mastermix, and uses a paper strip to display results. #STOPCovid can detect down to 100 copies of SARS-Cov-2 RNA from patient samples. 2/Xpic.twitter.com/vN6jT7QT2P

        6 replies 42 retweets 142 likes
        Show this thread
      3. Feng Zhang‏ @zhangf 5 May 2020

        Enabling testing at home and in low-resource settings requires that we can’t be reliant on complex instrumentation. #STOPCovid can be used with a sous-vide cooker (<$40). 3/Xpic.twitter.com/5nsH5Ivxcb

        6 replies 70 retweets 239 likes
        Show this thread
      4. Feng Zhang‏ @zhangf 5 May 2020

        Super proud of the #STOPCovid team, @JuliaJoung, @LadhaAlim, @omarabudayyeh, @jgooten, MSegel, MSaito, RMacrae, and EBlackwell who have worked tirelessly for achieving this advance. We are charging forward to develop this into a turn-key solution for at-home testing. 4/Xpic.twitter.com/emHwHxZpV0

        2 replies 22 retweets 123 likes
        Show this thread
      5. Feng Zhang‏ @zhangf 5 May 2020

        Last but not least, huge thanks to our supporters, in particular @HHMI, @McGovernMIT, @broadinstitute, @NIH, @open_phil, Mathers Fdn, J.&P. Poitras, M.&L.&E.Schwartz, and @NEBiolabs, @Quintara_Bio, @Synthego, & MileniaBiotec for their big help. 5/X

        2 replies 9 retweets 72 likes
        Show this thread
      6. Feng Zhang‏ @zhangf 5 May 2020

        We are making a limited number of research-use-only #STOPCovid reagents available for free to the research community. Updates to the protocol and data will be added to our website http://STOPCovid.science . Reagent request form: https://forms.gle/2cvBLt2gLKGQEtNL6 … 6/6pic.twitter.com/xOeTLdRMMK

        8 replies 48 retweets 144 likes
        Show this thread
      7. Feng Zhang‏ @zhangf 5 May 2020

        Also a huge thanks to our collaborators Keith Jerome & Alex Greninger at Univ Washington and Bruce Walker & Jon Li @MassCPR for access to patient samples!

        2 replies 10 retweets 66 likes
        Show this thread
      8. End of conversation
      1. New conversation
      2. Michael Glotzer‏ @Mglo 5 May 2020
        Replying to @zhangf @srikosuri and

        Do you have significant specificity concerns about RT-LAMP only assays? The data I have seen looks very good and the assay is even more simpler and requires fewer reagents.

        1 reply 0 retweets 3 likes
      3. Michael Glotzer‏ @Mglo 5 May 2020
        Replying to @Mglo @zhangf and

        Most positives from these field style tests would be referred for clinical testing in any case, so a low rate of false positives would seem to be an acceptable trade off for greater ease and lower cost.

        1 reply 0 retweets 6 likes
      4. Show replies
      1. New conversation
      2. Nathan Naze‏ @nanaze 5 May 2020
        Replying to @zhangf @jdf_ev

        23andC19

        1 reply 0 retweets 0 likes
      3. Nathan Naze‏ @nanaze 5 May 2020
        Replying to @nanaze @zhangf @jdf_ev

        https://www.nytimes.com/2020/05/05/health/crispr-coronavirus-covid-test.html …

        0 replies 4 retweets 8 likes
      4. End of conversation

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