Guess I need to watch the full interview but the reality is: 1) mRNA boosters do not have this performance feature, certainly not vs omicron, 2) you cannot scale mRNA to the level needed for global vaccinations, 3) there are better vaccines for this purpose and global healthhttps://twitter.com/alivelshi/status/1480214782779314182 …
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Replying to @PeterHotez
COI Disclosure: [Insert COI disclosure here] It's one thing to push your vaccine, but lets not throw other life-saving tech under the bus in the process.
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Replying to @jbakcoleman @PeterHotez
To be fair, he's responding to someone who's claiming that "only mRNA vaccines can bring an end to this pandemic." It's not bcs they perform better than AZ vaccine, that mRNA vaccines are intrinsically better, cfr. CureVac. And regarding scaling: why did 3rd world receive so few?
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Replying to @JorisMeys @PeterHotez
LMIC haven't had mRNA in large quantities because of a lack of political will, not some inherent property of mRNA vaccines.
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Replying to @jbakcoleman @PeterHotez
That and cold storage. Btw, I didn't read Hortez as "don't use mRNA" but as "don't diss other options that have proven to be far more valuable for 3rd world countries so far". He has a point there. "Only use (expensive, patented and fragile) mRNA" is not what 3rd world needs
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Replying to @JorisMeys @jbakcoleman
Many poorer countries have sufficient infrastructure for dealing with cold-storage, and more experience than us in distributing such vaccines. Cold chain requirements would not be much of an issue if we distributed the vaccines equitably globally. Very solvable if not solved.
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Replying to @zeynep @jbakcoleman
I didn't say it's impossible. I said it's an extra hurdle. mRNA vaccines aren't going to appear in sufficient amounts for the entire world in the coming year either. That's why it's silly to claim only mRNA and no other vaccines are helpful. Hortez rightfully objects to that.
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Replying to @JorisMeys @zeynep
I'd rather have us invest in mRNA or existing vaccines than try to reroute that energy/effort/funding towards a vaccine pushed by Hotez with no publicly available data, which is the subtext of his comments.
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Replying to @jbakcoleman @zeynep
And why exactly are we objecting to the only patent-free vaccine to date? In a perfect world we all had an updated mRNA vaccine for multiple variants available. Right now it looks those protein subunit vaccines are doing more for poor countries than mRNA will the coming years.
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I'm absolutely *not* objecting to any vaccine, let alone a patent-free one. I look forward to public data on it, especially since it's crucial for a vaccine aimed at poorer countries to be proven to be equal or superior to existing vaccines. Otherwise, catastrophic for trust.
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Replying to @zeynep @jbakcoleman
I reacted to Joe, but ok... So we do agree Hotez didn't throw anything under the bus and Keshavee was wrong claiming mRNA vaccines are the only ones that can stop the pandemic?
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