Genuine question. I once had a medical doctor who swore by saline nose/throat gargling for upper respiratory tract illnesses—he was a by the book, orthodox, evidence-based doc. I did not research it. Anyone know the evidentiary status of his claim? I did not see a recent review.
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Replying to @zeynep
Evidence is limited. Some pediatrics studies found
symptoms (2020) : https://pubmed.ncbi.nlm.nih.gov/32312677/
Evidence is weaker in adults (2015): https://pubmed.ncbi.nlm.nih.gov/25892369/
Pilot study in 2019 found
symptoms,
viral shedding, but larger studies required: https://pubmed.ncbi.nlm.nih.gov/30705369/ 1 reply 0 retweets 6 likes -
Replying to @AartikSarma
Yeah, seeing very little systematic evidence. Just got sent this for COVID-19; no control group really and tiny sample, but compares very well to larger national data. (Yes, not conclusive). I'm just surprised it wasn't studied more before.https://www.medrxiv.org/content/10.1101/2021.08.16.21262044v3 …
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Replying to @zeynep @AartikSarma
Look at my bibliography and references, I tried to be comprehensive. My concern with this method is that we missed the window of opportunity when SARS-cov-2 was almost exclusively nasal and TMPRSS2 only protease that worked.
1 reply 0 retweets 0 likes
Thank you. I’m just surprised there aren’t more/bigger trials on this. It’s one of those things that should be possible to test for, and why not?
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