Genuine question. I once had a medical doctor who swore by saline nose/throat gargling for upper respiratory tract illnesses—he was a by the book, orthodox, evidence-based doc. I did not research it. Anyone know the evidentiary status of his claim? I did not see a recent review.
You can't blind it unless you are testing the solution, but why not make one group do some other can't hurt intervention anyway? One group gargles, other group washes face, something.
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Sure, could work for a treatment study, like does this reduce complications for those already with URIs, as time course for intervention and study is short. But still expensive with the follow up (or reliance on self reports). Trying to study prevention would be even pricier
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But you’re right in that the barrier is more cost than science.
End of conversation
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