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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      zeynep tufekci Retweeted Muge Cevik

      See thread, explaining new study: much higher transmissibility for Omicron on top of antibody evasion causing more breakthroughs and re-infections. Do note that even if milder due to immunity and/or lesser intrinsic virulence, still crucial especially for elderly to get boosters.https://twitter.com/mugecevik/status/1471088936999137281 …

      zeynep tufekci added,

      Muge CevikVerified account @mugecevik
      Very interesting analyses about the virology of #Omicron, which may explain the faster spread of this variant. According to a new lab study, Omicron infects & multiplies ~70x faster than the Delta variant and the wild type SARS-CoV-2 in the human bronchus, but not in the lung.
      Show this thread
      11 replies 86 retweets 313 likes
      Show this thread
    2. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      Still more to learn but... Even lots of mild cases all at once with a small portion of severe cases—as we age, the T cell response is less robust, so breakthroughs can progress more readily—can cause a lot of suffering and overwhelm health-care system. Boosters demonstrably help.

      5 replies 15 retweets 93 likes
      Show this thread
    3. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      Plus, there are countries that successfully avoided big outbreaks, but are not fully done vaccinating their population let alone boosting due to supply issues. That makes them vulnerable and making sure they can boost especially their vulnerable populations is of utmost urgency.

      1 reply 6 retweets 71 likes
      Show this thread
    4. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      zeynep tufekci Retweeted Charre

      Don't have time to recap now (maybe there's a thread) but it's been clear even before Omicron, from high-quality randomized trials, that a third dose is really helpful, including against Delta but now against Omicron. Many vaccines are three-dose series.https://twitter.com/atheistsquid/status/1471121959186407430 …

      zeynep tufekci added,

      Charre @atheistsquid
      Replying to @zeynep
      On what basis are you pushing for boosters? You say they help, but based on what evidence?
      5 replies 6 retweets 77 likes
      Show this thread
    5. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      I think a three-dose primary series now, and a booster later preferably with something other than the ancestral spike but with prefusion stabilization, is quite likely where this may land, eventually. I want to emphasize this makes planning and global equity even more important.

      6 replies 11 retweets 90 likes
      Show this thread
    6. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      I'm hearing a lot of reports that, especially for elderly people, negotiating a booster is a problem in many states, with little appointment availability. The bottleneck seems to be logistics and staffing, not supply. At a personal level, check on your loved ones and neighbors!

      3 replies 8 retweets 85 likes
      Show this thread
      zeynep tufekci‏Verified account @zeynep 15 Dec 2021

      zeynep tufekci Retweeted TC

      You mean a bit like the flu? Maybe. Miraculous isn't it? Five minutes in a pharmacy and you have the upper hand against this virus, and in a better position than humans have ever been against infectious diseases. I'm in awe of such scientific achievements.https://twitter.com/cavallario/status/1471126023400050693 …

      zeynep tufekci added,

      TC @cavallario
      Replying to @zeynep
      What evidence? It could be a two-dose regimen with infinity boosters.
      6:37 AM - 15 Dec 2021
      • 33 Retweets
      • 395 Likes
      • Levi Thatcher Shir Goldbird Cat Cardenas Kristine Rudolph turn on Exposure Notifications on your phone Daniel Beardsall Patrick Boland Jenni Aloi Michaël Defferrard
      17 replies 33 retweets 395 likes
        1. New conversation
        2. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

          zeynep tufekci Retweeted Richard Van Noorden

          Great thread here on booster studies and existing data.https://twitter.com/Richvn/status/1471134533877743629 …

          zeynep tufekci added,

          Richard Van NoordenVerified account @Richvn
          Replying to @atheistsquid @zeynep
          That's the evidence for boosters in general -- which is strong. If you're asking about the evidence against omicron specifically (which came after that article), it's in here: https://www.nature.com/articles/d41586-021-03672-3 … . Pfizer data the strongest. (1/2)
          5 replies 6 retweets 57 likes
          Show this thread
        3. zeynep tufekci‏Verified account @zeynep 15 Dec 2021

          zeynep tufekci Retweeted Alex Selby

          A similar trajectory is possible here. UK is experiencing highest recorded number of cases *throughout the whole pandemic*. Rather than arguing over “mildness”, we should take steps now to mitigate the most plausible risks. More is different; faster is different.https://twitter.com/alexselby1770/status/1471154053031899145 …

          zeynep tufekci added,

          Alex Selby @alexselby1770
          Unfortunately it looks like London Omicron cases, already sky high in younger age groups, are now making their way into the older age groups too. We can expect the rest of the UK to follow London in a few days. Auto-updating case-by-ages graphs here: http://sonorouschocolate.com/covid19/index.php?title=CasesByAge … pic.twitter.com/gQ0CrezEkZ
          6 replies 83 retweets 160 likes
          Show this thread
        4. End of conversation
        1. New conversation
        2. TC‏ @cavallario 15 Dec 2021
          Replying to @zeynep

          I hope so. I just think putting a number on it and then going back on it makes it look like failure when it’s not. Better to prime for the possibility that it is like a flu shot.

          1 reply 0 retweets 2 likes
        3. zeynep tufekci‏Verified account @zeynep 15 Dec 2021
          Replying to @cavallario

          Yeah, agree and possible, but we just have the period in front of us for now, which needs global equity.

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. New conversation
        2. Jorge & the Kraken‏ @jorge_thekraken 15 Dec 2021
          Replying to @zeynep

          I am consistently flummoxed at the wailing and gnashing of teeth over the idea of annual/semi-annual shots. I felt like garbage for 36 hours after my second and third Pfizer doses, but I'd do it once a month if it meant getting the upper hand on this virus.

          2 replies 0 retweets 10 likes
        3. TC‏ @cavallario 15 Dec 2021
          Replying to @jorge_thekraken @zeynep

          Compliance/convenience is important in medicine. Just because you’re willing to do that doesn’t mean 80% of population is.

          2 replies 0 retweets 2 likes
        4. Show replies
        1. New conversation
        2. David Fry‏ @frydave 15 Dec 2021
          Replying to @zeynep

          "I exercised yesterday but now you say I have to exercise again, just to be healthy? When does this stop??"

          2 replies 5 retweets 20 likes
        3. brandon, but  ✨ stickers  ✨‏ @bdimcheff 15 Dec 2021
          Replying to @frydave @zeynep

          For real tho

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. Councilman Tony Heyl‏ @tonyheyl 15 Dec 2021
          Replying to @zeynep

          If you tell me that one or two shots a year will protect me from sickness and let me live my life freely, I'll jump at the chance. Sounds great to me!

          0 replies 0 retweets 3 likes
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        1. Nicholas Weaver‏Verified account @ncweaver 15 Dec 2021
          Replying to @zeynep

          Actually looking forward to Moderna’s in-testing Flu + COVID mRNA vaccine. Not just 1 shot but putting influenza under the same quick-change-pipeline is a design that can prevent the next pandemic influenza.

          0 replies 0 retweets 5 likes
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