See thread, explaining new study: much higher transmissibility for Omicron on top of antibody evasion causing more breakthroughs and re-infections. Do note that even if milder due to immunity and/or lesser intrinsic virulence, still crucial especially for elderly to get boosters.https://twitter.com/mugecevik/status/1471088936999137281 …
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I think a three-dose primary series now, and a booster later preferably with something other than the ancestral spike but with prefusion stabilization, is quite likely where this may land, eventually. I want to emphasize this makes planning and global equity even more important.
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I'm hearing a lot of reports that, especially for elderly people, negotiating a booster is a problem in many states, with little appointment availability. The bottleneck seems to be logistics and staffing, not supply. At a personal level, check on your loved ones and neighbors!
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You mean a bit like the flu? Maybe. Miraculous isn't it? Five minutes in a pharmacy and you have the upper hand against this virus, and in a better position than humans have ever been against infectious diseases. I'm in awe of such scientific achievements.https://twitter.com/cavallario/status/1471126023400050693 …
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Great thread here on booster studies and existing data.https://twitter.com/Richvn/status/1471134533877743629 …
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A similar trajectory is possible here. UK is experiencing highest recorded number of cases *throughout the whole pandemic*. Rather than arguing over “mildness”, we should take steps now to mitigate the most plausible risks. More is different; faster is different.https://twitter.com/alexselby1770/status/1471154053031899145 …
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Evidence summarised in this story cc
@atheistsquidhttps://www.nature.com/articles/d41586-021-03592-2 … -
The article that leads with there being no evidence of how effective it is against omicron yet summarizes the evidence it is effective against omicron?
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I'm glad that every adult in my family, including my wife and I and our parents, got boosters and our kids are fully vaccinated (now 6 & 7 years old). I encourage everyone to get their shots. Now we can see family and friends more safely.
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UK data will likely spell this relationship out soonest, from their Friday report we already were offered this glimpse into what they think they are seeing: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1040076/Technical_Briefing_31.pdf …pic.twitter.com/z02H3yiZh6
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I am skeptical that good evidence exists that boosters help against omicron, because I am skeptical it has been enough time to gather that data even if it is true. I greatly dislike that things are being pushed without evidence and skepticism is viewed as bad faith.
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