This! In Moderna RCT, 215/271 post-vax infections were asymptomatic. What are the chances those would get picked up in an observational study? Who would test for that? So it artificially shrinks denominator, making it seem as if little severity reduction.https://www.nejm.org/doi/full/10.1056/NEJMoa2113017?query=featured_home …
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I want to a textbook called “Mind the Denominator”, to be a whole semester a mandatory course series for anyone dealing with any statistical data. I used to teach intro to stats/methods etc. Social sciences call these selection effects. We talk about it, of course…
3 replies 4 retweets 30 likes
Replying to @zeynep @deeptabhattacha and
…But my experience over the pandemic is that we don’t talk about it enough. Things keep going back to this: not paying attention to the whole life-cycle of the data generation. Before asking what the data says, the first question should be a deep examination of “why this data?”.
5:26 AM - 10 Dec 2021
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3 retweets
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