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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Joseph Allen‏ @j_g_allen 5 Dec 2021

      Joseph Allen Retweeted Michael Mina

      Always surprised me that the ‘delayed 2nd dose’ convo got shut down hard and early when we started rolling out vax in 2020. For biological reasons it made sense, but also we had more arms than shots avail so would’ve gotten more protected, faster. Was a smart strategy, ignored.https://twitter.com/michaelmina_lab/status/1467374594063585282 …

      Joseph Allen added,

      Michael MinaVerified account @michaelmina_lab
      3-4 week spacing was never a biologically relevant window of time for maximum benefit. It was always used simply to speed up the trials, Else we would have had to wait months longer to start vaccinating ppl. We can’t keep confusing authorizations with biological optimum https://twitter.com/EricTopol/status/1467186981327151105 …
      Show this thread
      39 replies 57 retweets 421 likes
    2. John Skylar, PhD‏ @JohnSkylar 5 Dec 2021
      Replying to @j_g_allen @zeynep

      There were voices (like @michaelmina_lab) who called for a trial of this. They were ignored by both its detractors AND supporters; the latter wanted to just experiment on the public. At least now we have some data. It was right not to support doing this w/out data or a trial.

      2 replies 0 retweets 7 likes
      zeynep tufekci‏Verified account @zeynep 5 Dec 2021
      Replying to @JohnSkylar @j_g_allen @michaelmina_lab

      Thank you for explaining this, I had no idea.

      9:30 AM - 5 Dec 2021
      • 6 Likes
      • Dina D. Pomeranz Michael Mina Jim is Awesome Pablo Cotera Steve Greene
      2 replies 0 retweets 6 likes
        1. New conversation
        2. Joseph Allen‏ @j_g_allen 5 Dec 2021
          Replying to @zeynep @JohnSkylar @michaelmina_lab

          Joseph Allen Retweeted Joseph Allen

          Exactly…https://twitter.com/j_g_allen/status/1356413932114759685 …

          Joseph Allen added,

          Joseph Allen @j_g_allen
          More adding support for delayed 2nd dose strategy. @mtosterholm + @mlipsitch are supportive. Early calls to consider this (notably op-ed by @michaelmina_lab + @zeynep in mid-Dec) were too quickly dismissed by some, IMO. It's a race against new variants. https://www.cidrap.umn.edu/news-perspective/2021/02/experts-tout-delaying-2nd-covid-vaccine-dose-us-deaths-mount …
          1 reply 0 retweets 3 likes
        3. John Skylar, PhD‏ @JohnSkylar 5 Dec 2021
          Replying to @j_g_allen @zeynep @michaelmina_lab

          My point here is that the ones calling for doing it without a trial were calling for something that’s a real ethical violation. I’m afraid we are going to take away the lesson here that we should have just rolled this out without testing. I think that’s very, very wrong.

          1 reply 0 retweets 0 likes
        4. Show replies
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        2. Michael Mina‏Verified account @michaelmina_lab 5 Dec 2021
          Replying to @JohnSkylar @zeynep @j_g_allen

          I think we should have definitely had the trials - as we wrote. That said, we had a lot of data - it showed that at the very minimum efficacy was over 90% after a single dose up through a month. And so at least we knew 1 dose would be highly beneficial for at least 2-3 months.

          2 replies 0 retweets 4 likes
        3. Show replies
        1. New conversation
        2. John Skylar, PhD‏ @JohnSkylar 5 Dec 2021
          Replying to @zeynep @j_g_allen @michaelmina_lab

          I deleted my original reply here because I said something out of line. I was trying to make a point about the no-trials approach and couldn’t fit @zeynep’s name in the tweet. My regrets on that.

          1 reply 0 retweets 1 like
        3. Andy Schmidt‏ @andyaschmidt 6 Dec 2021
          Replying to @JohnSkylar @zeynep and

          UK was right to do this"without data". There was no data either way and we killed a lot of people. Although what I didn't understand at the time was that a variant like Delta could change the effectiveness of one dose but not two. But in that way data would have been out of date

          1 reply 0 retweets 0 likes
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