Here's the deal. The "booster" is turning out to be more than a boost for waning efficacy. It's both true that we should prioritize this globally—health-care workers and high-risk people everywhere first—and that it's a no-brainer at the individual level.https://twitter.com/zeynep/status/1460976854811262984 …
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I'm very sympathetic to the notion that we haven't been where we need to be with communication around many issues. But adjusting dosing schedule once data comes in from large-scale real-life implementation is routine. It's called Phase IV trials.https://twitter.com/SantaMonicaBorn/status/1460984114853474306 …
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Yep. A lot of childhood vaccines are three-dose primary series. Some have a few boosters, but most of them do not need annual ones. We don't yet know where this one will end up, but this seems like the least of our problems.https://twitter.com/sailorrooscout/status/1460985569668915200 …
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The one that interests me is Moderna’s mRNA flu vaccine, which includes a COVID booster as welL I’m already getting jabbed once a year against influenza, so why not?
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I think of something like the tetanus shot. Generally, three doses, no? Followed by one every 10 years or so.
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HPV vaccine for older adults, too. It’s totally fine.
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I don’t think it’s the “3” that’s the problem, it’s that it’s an infinite number and the booster would be more than annual since efficacy drops off within months. It’s fine as a stopgap on our way to better vaccines.
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What are you talking about? There's no determination that it's "infinite" or even annual. Read her whole thread willya. It may be that it takes 3 shots to be completely immunized (that applies to other vaccinations already). And if it needs periodic boosters so what.
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Wasn’t public’s expectations. No surprise there’s push back and further erosion of trust in medical establishment.
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Part of being a functioning adult is recognizing and accepting that reality doesn’t often meet our expectations.
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