“Fewer than 1% of patients taking the drug needed to be hospitalized and no one died. In the comparison group, 7% were hospitalized and there were seven deaths.” So promising that they halted the trial early. Pfizer, like Merck, *must* allow cheap generics for LMIC. No excuses.https://twitter.com/AP/status/1456576002457575427 …
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Yes, you can't make effective use of antivirals if the testing/detection regime is not in place. Best results were within three days of symptom onset, but even five days wasn't bad. Still, clearly, easy/cheap testing is a key component.https://twitter.com/toxchick42/status/1456595908989161475 …
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How about a moratorium on second-order effect speculation without viable, previously-demonstrated mechanism of sufficient effect size or empirical support: "It's good news but if people do <something people don't really do and would be minor if few did>, it will actually be bad."
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Is it practical to get to people in time to help worst outcomes. People seem to get into trouble with COVID by not realizing how it is til too late.
Thanks. Twitter will use this to make your timeline better. UndoUndo
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Would these antivirals have any effect on flu? RSV? Rhinovirus? I know there is no data to say. But would they be harmful in anyway? I guess what I am getting at is would there be harm in making it SOP during the pandemic to give these to anyone with symptoms getting tested?
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Do virus develop anti-viral resistance the same way bacteria develop antibiotic resistance?
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Folks! Not everyone responds well to vaccines—millions of immunocompromised people, to start with. It’s an unalloyed good to have more tools. This is great news!