“Fewer than 1% of patients taking the drug needed to be hospitalized and no one died. In the comparison group, 7% were hospitalized and there were seven deaths.” So promising that they halted the trial early. Pfizer, like Merck, *must* allow cheap generics for LMIC. No excuses.https://twitter.com/AP/status/1456576002457575427 …
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Definitely would love to see more details ASAP, but it was the independent panel of experts who halted the trial early because the results were so promising—this happens when the people overseeing it decide it is not ethical to hold back distribution.https://twitter.com/Capt3958/status/1456594122861600768 …
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Yes, you can't make effective use of antivirals if the testing/detection regime is not in place. Best results were within three days of symptom onset, but even five days wasn't bad. Still, clearly, easy/cheap testing is a key component.https://twitter.com/toxchick42/status/1456595908989161475 …
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How about a moratorium on second-order effect speculation without viable, previously-demonstrated mechanism of sufficient effect size or empirical support: "It's good news but if people do <something people don't really do and would be minor if few did>, it will actually be bad."
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Lots of old people haven't had a booster, either. With a huge Delta wave this winter, a working drug is very welcome.
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Jewish Chronicle editor
@stephenpollard has spoken about how he didn't develop antibodies from the vaccine due to cancer/treatment. Therapeutics (and prophylactic mabs?) vital for people in that situation.Thanks. Twitter will use this to make your timeline better. UndoUndo
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Really great news. If my vaccinated elderly parents get sick, I want every option open to help them. Anyone who is against new treatments in anyway are bonkers.
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Also, as silly as it sounds, there is likely a non-trivial portion of non-vaccinated people whose primary reason for not getting it is fear of needles.
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I think that a *huge* proportion of the unvaccinated are mainly just scared of needles. A certain proportion admit it (& should probably be offered benzos), & a larger portion are total babies who feel the need to spout conspiracy theories lest people find out they're afraid.
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Not to mention that pills are far easier to keep and transport around the world than vaccines needing to stay @ -40°
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That’s Pfizer only. Moderna is less difficult (-15 - -25C), AstraZeneca even more travel friendly (2 to 8C)
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Folks! Not everyone responds well to vaccines—millions of immunocompromised people, to start with. It’s an unalloyed good to have more tools. This is great news!