I see some making fun this development, comparing pills to vaccines, “will they take it, it’s not horse dewormer.”
Folks! Not everyone responds well to vaccines—millions of immunocompromised people, to start with. It’s an unalloyed good to have more tools. This is great news!
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Definitely would love to see more details ASAP, but it was the independent panel of experts who halted the trial early because the results were so promising—this happens when the people overseeing it decide it is not ethical to hold back distribution.https://twitter.com/Capt3958/status/1456594122861600768 …
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Yes, you can't make effective use of antivirals if the testing/detection regime is not in place. Best results were within three days of symptom onset, but even five days wasn't bad. Still, clearly, easy/cheap testing is a key component.https://twitter.com/toxchick42/status/1456595908989161475 …
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How about a moratorium on second-order effect speculation without viable, previously-demonstrated mechanism of sufficient effect size or empirical support: "It's good news but if people do <something people don't really do and would be minor if few did>, it will actually be bad."
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The group with 7 deaths was control. They didn’t get the Pfizer pill, they got whatever treatments exist now.
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Needs to be cheap as lots of people need to take it: "Patients who received the company’s drug [...] shortly after showing COVID-19 symptoms" and "Patients who received the drug earlier showed slightly better results, underscoring the need for speedy [...] treatment."
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Which is the tough part. Getting the sick person to be sampled & tested, let alone come forward early enough
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You know that isn’t happening. Pfizer etc wants the world to be forever reliant on Big Pharma so that their profits continue to grow.
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“Fewer than 1% of patients taking the drug needed to be hospitalized and no one died. In the comparison group, 7% were hospitalized and there were seven deaths.” So promising that they halted the trial early. Pfizer, like Merck, *must* allow cheap generics for LMIC. No excuses.