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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Alina Chan‏Verified account @Ayjchan 24 Oct 2021

      Alina Chan Retweeted Louis R Nemzer

      Looks like @voxdotcom might need to quietly edit its articles again in one year… Have your #OriginOfCovid reporters been paying any attention to the FOIA’ed and leaked EcoHealth-WIV research proposals and reports in the past 2 months?https://twitter.com/BiophysicsFL/status/1452265665818152966 …

      Alina Chan added,

      Louis R Nemzer @BiophysicsFL
      Dear @voxdotcom, Linking to the same controversial scientific article twice in a paragraph does not make something "we know for sure" "but we know for sure that the virus is not the product of deliberate gene editing in a lab..." @Ayjchan @R_H_Ebright https://www.vox.com/future-perfect/22734496/genetic-engineering-attribution-biosecurity-forensics-biological-detective-work …
      Show this thread
      13 replies 138 retweets 564 likes
      Show this thread
    2. Lab leak‏ @lab_leak 24 Oct 2021
      Replying to @Ayjchan @voxdotcom

      @KelseyTuoc is this your article? Hope you take note..

      2 replies 1 retweet 12 likes
    3. The Fall Guy‏ @fallguy9639 24 Oct 2021
      Replying to @lab_leak @Ayjchan and

      Scientific journal articles go through layers of peer-review before publication; where’s the review of a journalist’s product before making it to print?

      2 replies 3 retweets 17 likes
    4. Kelsey Piper‏Verified account @KelseyTuoc 24 Oct 2021
      Replying to @fallguy9639 @lab_leak and

      I'm the person who writes my content, and while I talk with tons of other people, I'm the person who gets it right or gets it wrong. I find the evidence that Covid-19 was not the product of deliberate gene-editing persuasive, so that's why I wrote that.

      14 replies 3 retweets 17 likes
    5. Alina Chan‏Verified account @Ayjchan 24 Oct 2021
      Replying to @KelseyTuoc @fallguy9639 and

      I don’t think this point is very clear, that it’s your personal opinion, in the article: “we know for sure that the virus is not the product of deliberate gene editing in a lab.”

      1 reply 9 retweets 96 likes
    6. Alina Chan‏Verified account @Ayjchan 24 Oct 2021
      Replying to @Ayjchan @KelseyTuoc and

      For the sake of avoiding misunderstandings, I think the article would be much better if it states that you personally believe that an engineered origin is not possible, But the scientific data available cannot tell us if SARS2 was genetically engineered.

      2 replies 8 retweets 83 likes
    7. Kelsey Piper‏Verified account @KelseyTuoc 24 Oct 2021
      Replying to @Ayjchan @fallguy9639 and

      I think "cannot tell us" is the wrong framework here. There are lots of things we'd expect to observe if SARS2 was genetically engineered and we have not observed any of them.

      10 replies 2 retweets 15 likes
    8. zeynep tufekci‏Verified account @zeynep 24 Oct 2021
      Replying to @KelseyTuoc @Ayjchan and

      What are those things? Curious that you seem to be more certain than Ralph Baric on this.

      1 reply 1 retweet 49 likes
    9. Alina Chan‏Verified account @Ayjchan 24 Oct 2021
      Replying to @zeynep @KelseyTuoc and

      Alina Chan Retweeted Will Bradshaw

      But also, even the scientist @willbradbio whose work is described extensively in this @voxdotcom story of whether Sars2 was genetically engineered, says that his work is not applicable to this question. Because we don’t have the tools to discern GE in Sars2.https://twitter.com/willbradbio/status/1452391367611756544 …

      Alina Chan added,

      Will Bradshaw @willbradbio
      I want to emphasise a distinction I think I didn't make clear enough before: Genetic engineering DETECTION = "Was this engineered?" Genetic engineering ATTRIBUTION = "Who engineered this?" You can't do GEA until you've done GED. Which is why GEA can't help us with COVID rn.
      Show this thread
      3 replies 2 retweets 29 likes
      zeynep tufekci‏Verified account @zeynep 24 Oct 2021
      Replying to @Ayjchan @KelseyTuoc and

      I just would like @KelseyTuoc to tell us what evidence would allow us to *rule out* genetic engineering of this virus to support the "we know for sure" wording in her article. Lots of people have *opinions* on likelihood of it, but I'm not aware of any that allows ruling it out.

      4:01 PM - 24 Oct 2021
      • 1 Retweet
      • 24 Likes
      • Purrtrand Russell (they/she/he) FVM Dominic Ryan Icaru The Seeker 🦧Dan Moulding🔭 kcz JoiningUnrelatedDots
      4 replies 1 retweet 24 likes
        1. New conversation
        2. Kelsey Piper‏Verified account @KelseyTuoc 24 Oct 2021
          Replying to @zeynep @Ayjchan and

          My present model looks like: there are some kinds of gene editing that would definitely be observable from the genome, and those are not observed; this was noticed early on and used to discredit other theories which it is not evidence either way on

          1 reply 1 retweet 5 likes
        3. Kelsey Piper‏Verified account @KelseyTuoc 24 Oct 2021
          Replying to @KelseyTuoc @zeynep and

          There are some convincing arguments that other gain-of-function-like work wouldn't be observable from the genome; serial passage might not be, and I'm agnostic about whether that occurred

          1 reply 1 retweet 4 likes
        4. Show replies
        1. New conversation
        2. Alex Crits-Christoph‏ @acritschristoph 24 Oct 2021
          Replying to @zeynep @Ayjchan and

          "The SARS-CoV-2 furin cleavage site does not match its canonical form (R-X-R/K-R), is suboptimal compared to those of HCoV-HKU1 and HCoV-OC43, lacks either a P1 or P2 arginine (depending on the alignment), and was caused by an out-of-frame insertion"https://www.cell.com/cell/fulltext/S0092-8674(21)00991-0 …

          1 reply 2 retweets 7 likes
        3. Alina Chan‏Verified account @Ayjchan 25 Oct 2021
          Replying to @acritschristoph @zeynep and

          “we have little insight to the viruses and virus sequences available to scientists and the experiments being conducted in labs prior to the detected Covid-19 outbreak — these would have a great influence on the types of insertions being made”https://ayjchan.medium.com/a-response-to-the-origins-of-sars-cov-2-a-critical-review-5d4a644d9777 …

          1 reply 1 retweet 4 likes
        4. Show replies

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