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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    zeynep tufekci‏Verified account @zeynep 18 Oct 2021

    zeynep tufekci Retweeted Michael Mina

    Finally. Also: Shape of global supply plus science has long suggested we do this globally. For real—prime with a vaccine with better supply like AZ, boost with Moderna/Pfizer.https://twitter.com/michaelmina_lab/status/1450223238659850241 …

    zeynep tufekci added,

    Michael MinaVerified account @michaelmina_lab
    Great news - science prevails! Boosting across vaccines will likely be formally authorized soon in the US. I love when the news is positive and the regulation follows the biology. Vaccines are being done right with this forthcoming announcement. https://www.nytimes.com/2021/10/18/us/politics/fda-mix-and-match-boosters.html …
    5:48 PM - 18 Oct 2021
    • 46 Retweets
    • 322 Likes
    • Peach's Mom 💉💉💉😷 Purrtrand Russell (they/she/he) Justice Ginsberg’s Umbrella Michael Mina Kuang-Yu Liu James Bradbury Alison Meaghan Kennedy Paquita Pichón
    8 replies 46 retweets 322 likes
      1. zeynep tufekci‏Verified account @zeynep 18 Oct 2021

        zeynep tufekci Retweeted zeynep tufekci

        Broader/faster with higher efficacy.https://twitter.com/zeynep/status/1405205426745102342 …

        zeynep tufekci added,

        zeynep tufekciVerified account @zeynep
        Yes, ideally, we increase supply of the highest efficacy ones. Maybe AZ prime/mRNA booster can be considered, as @dylanhmorris was pointing out—fits the shape of the supply better. Maybe subunit ones are easier to scale up production. But this is key: time is of the essence here.
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        1 reply 2 retweets 56 likes
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      1. James Scheibner‏ @ScheibnerJames 18 Oct 2021
        Replying to @zeynep

        It would help, of course, if some vaccine manufacturers were less belligerent re bilateral licensing agreements and we could ramp up manufacturing.

        0 replies 0 retweets 7 likes
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      2. Zoë McLaren, PhD‏ @ZoeMcLaren 18 Oct 2021
        Replying to @zeynep

        Everyone saying that J&J “should have” made it a 2-shot vaccine forget that it was designed in part to help vaccinate the entire world. J&J or AZ prime followed by mRNA is a great strategy to control the pandemic in LMICs.

        2 replies 0 retweets 28 likes
      3. Andrew Lowry‏ @AndrewJLowry 18 Oct 2021
        Replying to @ZoeMcLaren @zeynep

        We used AZ prime w mRNA second dose spread out 8 to 16 weeks in Canada this year due to supply issues. It has worked great. We also mixed mRNA. Glad to see the USA FDA accept it.

        1 reply 1 retweet 23 likes
      4. Show replies
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      2. drGarthK‏ @DrGarthK 18 Oct 2021
        Replying to @zeynep

        Something nobody has looked at is to prime with Pfizer or Moderna & boost with AZ. I would love to hear some expert opinions on this: possible benefits include more rapid distribution due to good supply, & maybe good VE due to heterologous effects. But evidence needed of course.

        1 reply 0 retweets 1 like
      3. Ducky Sherwood  🦈 💉 💉‏ @duckysherwood 18 Oct 2021
        Replying to @DrGarthK @zeynep

        There have been a few studies, e.g. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01694-9/fulltext … That found AZ@1/AZ@2 < Pfizer/AZ < AZ/Pfizer < Pfizer/Pfizer in test tubes. You really wanted to have Pfizer second, and having it for both was even better.

        1 reply 1 retweet 3 likes
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      2. Ira Goldman  🦆 🦆 🦆‏ @KDbyProxy 18 Oct 2021
        Replying to @zeynep

        But do they have data for mix & match using only a half-dose of Moderna?pic.twitter.com/Jrit0yju95

        1 reply 0 retweets 1 like
      3. The Dose of Reality‏ @TheDoseTweets 18 Oct 2021
        Replying to @KDbyProxy @zeynep

        No, they don’t.

        0 replies 0 retweets 0 likes
      4. End of conversation
      1. Andy McCrea‏ @andymccrea 19 Oct 2021
        Replying to @zeynep

        Um, hi, 🇨🇦here…

        0 replies 0 retweets 0 likes
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