Do people know that the 1890 pandemic was likely caused by another coronavirus, OC43 (that was then novel?) Nowadays, no longer novel, it is one of the causes of the common cold. We're obviously not living in the OC43 pandemic since, and we won't live in a COVID pandemic forever.
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Replying to @zeynep @VoiceOfFranky
I thought it was an H2 flu? That's fascinating...is this based on banked sera?
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Replying to @DFisman @VoiceOfFranky
No banked sera paper that I know of, so no evidence for it being flu either. But the OC43 hypothesis looks stronger to me. (Also look at NL63: we weren't looking, just like people weren't looking at respiratory/aerosol spread and assumed droplets imo)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252012/ …
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Also 1890 was anosmic (and thus neurotropic, which we don't see for influenza in humans). I'd say pretty likely!https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/1751-7915.13889 …
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Dr. Swapneil Parikh 💉 💉 😷 Retweeted Dr. Swapneil Parikh 💉 💉 😷
The similarities based on historical clinical records are fascinating
https://twitter.com/swapneilparikh/status/1422647997809057792 …Dr. Swapneil Parikh 💉 💉 😷 added,
Dr. Swapneil Parikh 💉 💉 😷Verified account @swapneilparikhWas the 1889 to 1891 pandemic due to HCoV-OC43? Multi-system involvement (respiratory, GIT & neurological, loss of taste and smell, protracted recovery resembling long covid, thrombosis in multiple organs. Mortality mainly in elderly, children spared. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/1751-7915.13889 …1 reply 3 retweets 19 likes
Yeah, fascinating. Of course we should remain open to contra evidence but a lot of things are pointing in the same direction.
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