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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @Ayjchan @trvrb and

      Let's look at Dr Shi's papers. "The major differences in the sequence of the S gene of 2019-nCoV are the 3 short insertions in the N-terminal domain as well as changes in.. key residues in the receptor-binding motif compared with the sequence of SARS-CoV"https://www.nature.com/articles/s41586-020-2012-7#change-history …

      1 reply 1 retweet 7 likes
    2. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @Ayjchan @trvrb and

      Paper 2: Even after aligning spike, they didn't see the new FCS insertion. "aligning 2019-nCoV S protein sequence with those of SARS-CoV and several bat-SL-CoVs, we predicted that the cleavage site for generating S1 and S2 subunits is located at R694/S695" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033706/ …

      1 reply 1 retweet 5 likes
    3. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @Ayjchan @trvrb and

      Furthermore, all 3 authors on this paper had been part of a collaboration engineering an S1/S2 FCS into a MERS-like CoV (pseudotyped) in 2015.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524054/ …

      2 replies 1 retweet 12 likes
    4. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @Ayjchan @trvrb and

      I'm not saying this is a smoking gun for SARS-CoV-2 being engineered. But as @zeynep pointed out, it should at least be considered as an oddity.

      2 replies 2 retweets 11 likes
    5. zeynep tufekci‏Verified account @zeynep 10 Jun 2021
      Replying to @Ayjchan @trvrb and

      Oddity, but not a coverup. You have to assume people with this much expertise understand not explicitly mentioning it in that paper isn’t going to be a coverup, given genome already available and everyone will go 👀 as soon as they see it. Coverups have to make sense in context.

      1 reply 2 retweets 8 likes
    6. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @zeynep @trvrb and

      It could be a mistake omission due to panic (despite very carefully picking out nearby insertions and even looking at the very site compared to other SARSrCoVs in their collection). Or it could be a situation where they could not draw attention to it.

      3 replies 1 retweet 6 likes
    7. Alina Chan‏Verified account @Ayjchan 10 Jun 2021
      Replying to @Ayjchan @zeynep and

      Someone told me an anecdote about scientists in the West told not to speak about impt details of a discovery which were potentially dual use. But the scientists fought back, pointing out that the omission would draw attention. In China, can scientists push back against the gov?

      3 replies 3 retweets 11 likes
    8. Roger Pielke Jr.‏Verified account @RogerPielkeJr 10 Jun 2021
      Replying to @Ayjchan @zeynep and

      Roger Pielke Jr. Retweeted Roger Pielke Jr.

      Oddities are overdetermined in that available evidence allows many possible explanations That is why considering multiple oddities in context together is important A key element here is the Chinese gov’t stating that it views research publications as moves in a game of chesshttps://twitter.com/RogerPielkeJr/status/1401540854368522244 …

      Roger Pielke Jr. added,

      Roger Pielke Jr.Verified account @RogerPielkeJr
      This is the most remarkable new information I learned from it Chinese government views the publication of scientific research on COVID-19 like “moves in a game of chess” pic.twitter.com/TsptejuFGj
      Show this thread
      1 reply 1 retweet 7 likes
    9. zeynep tufekci‏Verified account @zeynep 10 Jun 2021
      Replying to @RogerPielkeJr @Ayjchan and

      Well fine but it would be a very stupid move in a game of chess not to mention the thing that’s already publicly available *and* very noticeable, on the theory that will be enough to bury it? Stupider things have happened but you have to acknowledge this is what it would mean.

      5 replies 1 retweet 4 likes
    10. Roger Pielke Jr.‏Verified account @RogerPielkeJr 10 Jun 2021
      Replying to @zeynep @Ayjchan and

      Well, the whole pangolin episode followed exactly this series of "stupid moves" (and it was uncovered as a result) As someone who has spent a lot of time looking at issues of bad science in politics, stupid moves are pretty common

      1 reply 0 retweets 3 likes
      zeynep tufekci‏Verified account @zeynep 10 Jun 2021
      Replying to @RogerPielkeJr @Ayjchan and

      As I said, stupider things have happened. And it is odd. But purposefully not mentioning the thing everyone would notice because it had already become public and was also obviously very noticeable seems especially stupid. You have to assume the scientists would point that out.

      1:41 PM - 10 Jun 2021
      • 1 Like
      • halvorz ¯\_(ツ)_/¯
      2 replies 0 retweets 1 like
        1. New conversation
        2. zeynep tufekci‏Verified account @zeynep 10 Jun 2021
          Replying to @zeynep @RogerPielkeJr and

          You also have to have a sociological theory of a coverup. It’s the clumsy & scientifically illiterate censors? How do they know this is significant and will raise eyebrows *and* also think not mentioning it solves the problem when it’s already public. As I said, one or the other.

          2 replies 0 retweets 1 like
        3. Roger Pielke Jr.‏Verified account @RogerPielkeJr 10 Jun 2021
          Replying to @zeynep @Ayjchan and

          On what basis do you assume censors are scientifically illiterate? Internal Chinese guidance on vetting research says the opposite Whether, with hindsight, any of us thinks this "chess move" was smart, dumb, intentional, oversight ... bottom line is that all we can say is "odd"pic.twitter.com/PuFEHITIbS

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. Roger Pielke Jr.‏Verified account @RogerPielkeJr 10 Jun 2021
          Replying to @zeynep @Ayjchan and

          Well, it was only 42 days from that paper (Feb 3 to Mar 17) until an analysis was published explaining the FCS as natural, making the oversight moot (in theory) If the goal was delay/muddy waters then looks a whole lot less stupid - when was significance of FCS first noted?

          0 replies 0 retweets 0 likes
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