Everyday I hear about someone very young in India, in the best of health, dying or critically ill with COVID. In many, the clinical course is one of rapid progression. Added to what's going on in the UK, makes me nervous about B.1.617 variants. Get vaccinated. That does work.
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Ask anyone in India, and most will know of someone like this. It's real.
12 replies 12 retweets 196 likesShow this thread -
In some one can blame lack of resources or steroid related complications. But in most it's pretty significant lung damage due to COVID.
#GetVaccinated4 replies 18 retweets 164 likesShow this thread -
Vincent Rajkumar Retweeted Dr. Nitin Shinde
This is what I'm hearing as well.https://twitter.com/DrNitinShinde5/status/1398232139406012418 …
Vincent Rajkumar added,
Dr. Nitin Shinde @DrNitinShinde5Replying to @AnuragAgrawalMD @james_oaten and 5 othersClinically We are seeing 1. Severe lung fibrosis & cavitation in lungs . 2. Aggressive cytokine storms in young people without comorbid conditions 3. Severe hyperglycemia (even in non diabetics with or without steroids ) 4. Persistent delayed inflammation beyond 1 month.1 reply 35 retweets 111 likesShow this thread -
In many cases, the severe lung damage and vascular events are happening despite the doctors doing the best they can. It's a feeling of being defenseless against this virus. We've seen similar incidents in the US, but the scale at which it is occurring in India is something else
3 replies 18 retweets 117 likesShow this thread -
Vincent Rajkumar Retweeted Siddhartha Mukherjee
Vincent Rajkumar added,
Siddhartha MukherjeeVerified account @DrSidMukherjeeImportant editorial on the very dangerous B1617 strain. Note: the vaccines in the US are likely protective against this strain. Please get vaccinated https://www.nytimes.com/2021/05/28/opinion/covid-vaccine-variants.html#click=https://t.co/FZsew6AZg9 …3 replies 18 retweets 83 likesShow this thread -
In my opinion, in addition to the "increased transmissibility is an exponential threat" described by
@zeynep, the severity in young people in India, & the frequent occurrence of 2 or more young people in same family critically ill or dying indicates increased virulence as well.6 replies 27 retweets 102 likesShow this thread
Definitely can’t rule it out, though I couldn’t find a way yet to disentangle, statistically, from hospital collapse. Terrible enough either way but yes, can be worse if also increased severity which is definitely possible and anecdotally suggestive. 
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