Also note that even a slightly reduced efficacy in a vaccine’s ability to prevent mild symptoms does not imply an inability to prevent severe illness or death, and 75% efficacy for any symptoms whatsoever is way higher than anything many had realistically hoped for last year.
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Let me emphasize. This was not a precise number provided in a precise manner. For all I can tell from how it went down, he might’ve meant his estimate for minimum efficacy. Regardless, he immediately said don’t really know yet, and we’ll know better in a few weeks. No news here.https://twitter.com/zeynep/status/1395819531680075778 …
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What about the most important % -- efficacy against serious disease/hospitalization/death?
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Whoah, that's for symptomatic illness? Worse than I thought.
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how can they know without real world trials? is this real world trial or in the lab?
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I’m I crazy or is 75% still very good?
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75% is still very good in my opinion. I think we got spoiled by the 94/95% from the wild type. dont get me wrong, would like 100% but before we had even 1 vaccine the experts would have been happy with 60%.
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It would be nice if all the vaccine conversation focused on absolute (vs. relative) risk reduction, as well as Number Needed to Treat.
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Is it possible he is talking about reduction in antibodies not actual protection against illness? He goes from the 25-30 percent number on the antibody testing to the 70-75 percent number.
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What's Efficacy best understood as. 1. Efficacy in avoiding serious infection 2. Efficacy in avoiding serious illness.
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