SARS-CoV-2 vaccines substantially reduce transmission through 2 mechanisms:
(1)
chance of infection (regardless of symptoms
(2)
transmission potential of infected vaccinee
Our new review of the overwhelming evidence
@mugecevik @EricMeyerowitzhttps://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofab259/6278371 …
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The exact amount of reduction in transmission is not known but I think evidence suggests at minimum 80% and probably much higher -> -Minimum 60% reduction in infections -Minimum 50% reduction in transmission potential
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Replying to @AaronRichterman
Ah excellent! Thank you all! I think the epidemiological dynamics do hint at higher numbers. Fingers crossed. I guess we will know better in late Fall when seasonality may reverse but it’s been quite promising and I already had thought the trial numbers were super encouraging.
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Yeah. I’ll read your paper. But one question that will come up a lot is how vaccine efficacy for symptomatic disease relates to transmission dynamics. I think we will have a clearer answer for the ones approved in the US or Europe/UK. Just more data. Not sure yet about others.
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