This is not a good answer. The result will be an inaccurate picture of the spectrum of severity in breakthrough cases, and a failure to capture the full benefits of vaccination in terms of severe infections averted.https://twitter.com/DrLeanaWen/status/1394666390242611203 …
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Replying to @BillHanage
Wait, what? That's, well, the "perfect" set up for nonstop freak-outs over breakthroughs that do not deserve panic (positive uncovered during mandatory/frequent testing in colleges/teams etc.) but also waiting till too late to recognize antigenic evolution of consequence?
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Replying to @zeynep @BillHanage
While knowing what's driving breakthroughs is of academic interest - in the context of mass vaccination and minimal healthcare utilization - is it overall important? Would it not be more advisable to use the hospitalized sample set to represent community from a resource point?
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Replying to @zchagla @BillHanage
It is of academic interest *and* to curb the unnecessary freak-outs. I am ready to pre-file my piece on "no, that vaccine breakthrough cluster at University X that tests all students weekly is not a cause for concern" article for Fall of 2021. I'd rather not write it, tbh.
1 reply 1 retweet 15 likes -
zeynep tufekci Retweeted zeynep tufekci
I finally got
@dylanhmorris to write this piece for my newsletter. Essentially, there really isn't a lot of understanding out there on what a vaccine breakthrough means and does not mean, and why, for example, variants don't set us back to March 2020.https://twitter.com/zeynep/status/1394654982692122627 …zeynep tufekci added,
zeynep tufekciVerified account @zeynepToday's@insight is a brilliant guest essay by@dylanhmorris explaining why novelty of this pathogen is so deeply related to everything we've been wondering about: variants, vaccine breakthrough cases, children, Long Covid, endemicity and more. https://www.theinsight.org/p/novelty-means-severity-the-key-to … pic.twitter.com/mMuVVAwd4QShow this thread1 reply 0 retweets 5 likes
I think better surveillance of breakthroughs will both be informative (in case a bad surprise is brewing and we need to booster up) and help reassure the public that we are on top of it. The latter is not a secondary goal while we try to move out of the acute phase of all this.
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How well-defined are "breakthrough" infections? That is, if you have an infection that your body fights off promptly and without symptoms, is there a clear-cut line between infected and not-infected?
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