Fascinating preprint (H/T @zeynep ) - in host diversity is quite limited (i.e. variants aren't emerging from typical infections spreading)
This really brings up the concept of making sure our immunocompromised patients are followed up appropriately, and vaccines are pushedhttps://twitter.com/KATarinambraun/status/1388312255222124544 …
Great visual chart! But doesn't seem address use of convalescent plasma or monoclonal antibodies especially for immunocompromised patients. Hope soon. Especially the latter is... just used in a "what's the harm" kinda way.
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For sure - the FDA I believed just revoked EUA for BAM for this particular reason. But you're right no one has put a practice point out there (outside some of the discussion in NIH) and certainly nothing on how to treat/monitor pts with severe immunocompromised.
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Yeah, something on clinical practice on all this would probably be pretty useful now. (More so than just scary headlines about variants... Here's one thing that really can spring new ones for which we need globally accessible clinical guidance!) Did you say one was coming soon?
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We deep seq’d
carefully at long-term infxs.
1/12