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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Eric Topol‏Verified account @EricTopol 22 Apr 2021

      With addition of the new reports yesterday, the "breakthrough" infection rate after full mRNA vaccination has been consistently below 1%. Most are without symptoms, only detected by testing. Not included is the CDC report of 0.008% among 66 million people (no reference)pic.twitter.com/gJ4LJ3eAns

      30 replies 461 retweets 1,301 likes
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    5. zeynep tufekci‏Verified account @zeynep 22 Apr 2021
      Replying to @jonahfleish @EricTopol

      The six studies he's citing aren't efficacy studies, they are breakthrough studies. That's different from your example. As usual, Eric is doing very valuable work pulling together various studies to present an aggregate picture. (Honestly would say it if I disagreed with him!)

      1 reply 0 retweets 4 likes
    6. zeynep tufekci‏Verified account @zeynep 22 Apr 2021
      Replying to @zeynep @jonahfleish

      Post widespread vaccination, the kind of studies you can do are different compared with the trial period, and breakthrough rates tell us important things for sure, and we'll soon get numbers from around the world as well. So the numbers are informative in their own context.

      1 reply 0 retweets 1 like
    7. Jonah Fleishhacker‏ @jonahfleish 22 Apr 2021
      Replying to @zeynep

      Thank you, those are good points. I agree that aggregating the studies is incredibly valuable, but how can you compare those breakthrough rates side by side? The CDC rate has an entirely different meaning than a single event nursing home rate.

      1 reply 0 retweets 2 likes
      zeynep tufekci‏Verified account @zeynep 22 Apr 2021
      Replying to @jonahfleish

      Such definitonal alignments will happen, too but what we are learning is that breakthroughs are fairly miniscule compared to protectiveness (also the hospitalization/death matters). IMO the CDC number is the most informative, and, crucially that they are aligned is informative.

      3:52 PM - 22 Apr 2021
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      • Jerry Alexandratos 🇺🇸
      1 reply 0 retweets 1 like
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        2. zeynep tufekci‏Verified account @zeynep 22 Apr 2021
          Replying to @zeynep @jonahfleish

          In other words, that collection matters because it's showing you that the numbers aren't all over the place. The alignment is informative (the way Pfizer/Moderna trial number alignment was informative). We will learn more soon enough.

          1 reply 0 retweets 1 like
        3. Jonah Fleishhacker‏ @jonahfleish 22 Apr 2021
          Replying to @zeynep

          I mean, the highest number in that table is 100x higher than the CDC figure. Pfizer and moderna were within a few percent. I just think overall breakthrough rate isn’t a very informative metric.

          1 reply 0 retweets 1 like
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