The situation in India is dire and all variants associated with a surge need attention. But this man is 88 years-old, diabetic, two prior heart surgeries, and still had only mild symptoms (mild fever was reported) and is hospitalized out of caution likely because he is former PM.https://twitter.com/GabrielScally/status/1384452978086596616 …
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Yeah exactly. What I interpreted, anecdotally, as a story about how good these vaccines are turned into something people are sharing as concern about the vaccines. https://twitter.com/ac8786/status/1384871597299937282 …
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Given the depth of India's crisis, maybe we can reflect a bit on how much of the focus has been on the potential, speculative threat to us in the vaccine-rich wealthy countries (VARIANTS ON PLANES!) rather than what can we do, immediately, to help them.
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My guess: No "escaped a catastrophe before" is a guarantee, and our explanations were too speculative. I think neither Brazil nor India had herd immunity (seroprevalence studies weren't random) and *every* nonimmune (unvaccinated) population is under risk. https://twitter.com/korystotesbery/status/1384874124376514562 …
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We don't have to wait for full details of variant analyses or focus on potential effects here to recognize this: the crisis in India is really, really, really dire and has the potential to be the worst case in the world. Our lack of robust global response is heartbreaking.
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I can't see any published data other than phase II data against b117 UK strain? We also need control data to interpret vaccine effectiveness which is missing in that table.
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Covaxin had interim phase III data out for more than a month, and more were announced this morning.https://timesofindia.indiatimes.com/india/bharat-biotech-announces-phase-3-results-all-you-need-to-know/articleshow/81312912.cms …
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How are these numbers normalized/controlled?
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These numbers mean nothing without a control for the baseline infections among unvaccinated. Could be very good or very bad.
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This doesn't look like trial data (unlikely that crores were followed up in a trial), and given the known undertesting in India, & underreporting it's very likely that these are underestimates. We definitely need to see the control group.
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I'd also like more data. But US vaccine breakthroughs are also rarer than even my best hopes tbh. We'll see. That said, India's current, immediate and horrifying crisis does not seem to center around vaccine breakthroughs, and seems to deserve action regardless.pic.twitter.com/IKmA2VUShe
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