btw, regarding recent remarks by Pfizer's CEO that it's "very likely" we'll need a third shot "within 12 months" or that yearly boosters will be : i strogly think this to be absolute nonsense. two shots will very likely prove lifelong protection for anyone that's immuocompetent.https://twitter.com/wanderer_jasnah/status/1383675004194226180 …
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Replying to @wanderer_jasnah
What about gradual loss of immunity to common hCoVs?
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Replying to @iskander @wanderer_jasnah
I’d take a look at this paper by
@jbloom_lab. More of an issue of antigenic drift than waning of functional immunity.https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009453 …1 reply 1 retweet 7 likes -
This is the paper I was thinking of. If 1 year of SARS-CoV-2 buys the virus some lineages with order of magnitude decreases in neutralization, what happens after 10 years?
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Replying to @iskander @deeptabhattacha and
We find out the true shape of the fitness landscape? 
1:25 PM - 18 Apr 2021
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