I hope so. I read tweet Crotty had about some awesome vax number we had. First comment was basically we are going to cause ADE and an escape mutant. I don’t know where all this comes from but it’s every single thread some far out worry.
-
-
And I worry it's exacerbating the biggest risk, which is that not enough people get vaccinated. It would be perverse if the fear that vaccines don't work well enough against variants means that not enough people get vaccinated for them to work well against variants.
2 replies 0 retweets 23 likes -
Most of the time when I get a reply like this, the replier refers to EFD. So I'm forced to conclude that he's driving a huge part of the conversation here. He has the reach and he makes more noise than anybody.
3 replies 0 retweets 38 likes -
I have come to the same conclusion. Over and over again that particular "expert" (who is actually not well-credentialed in terms of infectious disease) has referred to variants as completely "escaping" immunity. Antibody neutralization is not synonymous with functional immunity.
7 replies 7 retweets 80 likes -
Replying to @angie_rasmussen @notdred and
That part is certainly true. That said, I'm not highlighting others (point isn't to create social media pile-ons) but I've seen versions of: completely escaping/useless/renders ineffective pretty broadly claimed, on TV/media/here (by credentialed folks).
1 reply 0 retweets 26 likes -
I have too, but I have to say most virologists/immunologists/vaccinologists/ID epis/ID physicians I've seen take pains to get this right. They can be misquoted, which is also a problem. It's hard to explain that PRNT50 assays don't translate to functional immunity.
1 reply 0 retweets 26 likes -
Replying to @angie_rasmussen @notdred and
zeynep tufekci Retweeted WebMD
Yeah. Example of what many ordinary people are seeing. I mean, sure, let's not let this @#!! freely explore the full fitness landscape through an unchecked epidemic—and we have boosters in the works—but what on earth? (It comes from an ill-sampled survey).https://twitter.com/WebMD/status/1377417935703052292 …
zeynep tufekci added,
1 reply 0 retweets 19 likes -
I especially loathe the trend of polling a non-random sample of (insert experts here) and presenting it as if it's a reliable forecast of what's to come. Certainly new variants are a possibility, but that's not set in stone. We can do something about that!
2 replies 1 retweet 28 likes -
Replying to @angie_rasmussen @zeynep and
This would be much more productive if we focused messaging on the actions we can take to mitigate the risk of new variants emerging: reduce transmission, increase immunization.
2 replies 1 retweet 36 likes -
Replying to @angie_rasmussen @zeynep and
And I am very suspicious of the actual expertise of anyone who thinks variants will evolve that can completely circumvent the totality of the immune response next month/quarter/year.
5 replies 10 retweets 92 likes
Yep! I don't like the "I'll that bet" things, because it seems like a stunt, but I'd take a five figure bet (for a global health charity of anyone's choice) against the prediction variants making vaccines "ineffective" (circumventing totality of immune response) in the next year.
-
-
Same. And even if that were to somehow happen, defying *checks notes* the entire history of vaccines, we can easily make boosters. While there is a bit of a problem with minimizing variant concerns as well, the idea that this would happen before we could respond is not realistic.
6 replies 1 retweet 71 likes -
Replying to @angie_rasmussen @zeynep and
I've been trying to convey the concept of correlates of protection, which we haven't defined yet for these vaccines. Because antibody neutralization is generally important, people treat it as if it's an established correlate of protection. It's not. But hard to explain.
2 replies 1 retweet 25 likes - Show replies
New conversation -
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.