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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      I've realized many have the incorrect mental model of the immune system: we conceive of it as a protective wall with a fixed height, and assume that vaccine efficacy represents that height. Wrong. I wrote a post explaining what trials do and don't measure. https://zeynep.substack.com/p/vaccine-efficacy-statistical-power …pic.twitter.com/zXKrWKUSLA

      8 replies 154 retweets 804 likes
      Show this thread
    2. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Do I want high efficacy numbers? Of course. But efficacy in trials only pertains to symptomatic COVID. Vaccines also work on other parts of the immune system that kick in only after infection takes hold (disease) but can prevent progression to severe disease and hospitalizations.

      3 replies 83 retweets 742 likes
      Show this thread
    3. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Why do trials measure symptomatic COVID and report that as efficacy? Faster, easier. Why do many studies measure parts of the immune system that prevent symptoms but not the rest? Same. That's why real life trial data > lab studies freaking everyone out. https://zeynep.substack.com/p/vaccine-efficacy-statistical-power …pic.twitter.com/WhTKkw6vsO

      4 replies 88 retweets 606 likes
      Show this thread
    4. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      I'm grateful to the scientists doing their job and worrying about, studying and developing boosters against variants. The rest of us should focus on vaccinating the world as fast as possible, and especially what more transmissible/severe variants mean for the *unvaccinated.*

      4 replies 102 retweets 772 likes
      Show this thread
    5. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Let me add: as vaccination scales to millions there will be some "breakthrough" cases—even few severe ones, especially among the elderly. Even common colds can cause deadly outbreaks in nursing homes. But every piece of real life data so far looks great. https://www.theatlantic.com/health/archive/2021/03/fourth-surge-variant-vaccine/618463/ …pic.twitter.com/k6L9BH4ulC

      6 replies 116 retweets 691 likes
      Show this thread
    6. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Folks asking: We already know the two mRNA vaccines also overwhelmingly cut down any infection, including silent asymptomatic ones, *and* studies indicate even breakthrough disease after vaccination has lower viral load (hence likely less infectious). https://www.theatlantic.com/health/archive/2021/03/fourth-surge-variant-vaccine/618463/ …pic.twitter.com/EdWaVcmkxp

      6 replies 120 retweets 683 likes
      Show this thread
    7. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      zeynep tufekci Retweeted Rick

      Yeah. I constantly hear people invoke "immune evasion" (almost always a partial indication from studies that do not pertain to the whole immune system) as if it means vaccines becoming useless against variants. No! Anyway, let's vaccinate the world, ASAP.https://twitter.com/ricksterps/status/1379078510350860289 …

      zeynep tufekci added,

      Rick @ricksterps
      I wish we weren't allergic to good news involving covid. A lot of really positive data coming out recently. If I just read headlines I would believe the vaccines won't protect me from all the variants and they are only good for like 6 months. https://twitter.com/zeynep/status/1379064102824316929 …
      Show this thread
      15 replies 94 retweets 635 likes
      Show this thread
    8. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      zeynep tufekci Retweeted Nate Silver

      Let's put this here, but keep in mind: tens of millions in the US remain unvaccinated and are *just as much at risk* if infected (if not more, as some variants may also be more deadly). Vaccines are amazing, but the work is to vaccinate everyone, globally.https://twitter.com/NateSilver538/status/1379090275969216519 …

      zeynep tufekci added,

      Nate SilverVerified account @NateSilver538
      Just 222 COVID deaths reported in the US yesterday, which is the fewest since March 23, 2020. https://ourworldindata.org/covid-deaths  pic.twitter.com/FAyvg7tp4Z
      10 replies 111 retweets 589 likes
      Show this thread
    9. zeynep tufekci‏Verified account @zeynep 6 Apr 2021

      Flabbergasted at how much speculative worrying there is out there against current/future variants making our vaccines completely “ineffective” (I’ll easily take a bet against that) when the real issue is we have AMAZING vaccines that DO work, but not enough of them for the world!

      41 replies 198 retweets 1,134 likes
      Show this thread
    10. zeynep tufekci‏Verified account @zeynep 6 Apr 2021

      Common misleading headline/frame. Denominator is 1,800,000. That's ~1 in 10,000 breakthrough cases. Two, such cases are milder. Three, rare deaths, among the elderly happen at that scale. *Common colds* cause deadly outbreaks in nursing homes. And, only two were fully-vaccinated.pic.twitter.com/sCaNxh32xH

      7 replies 76 retweets 320 likes
      Show this thread
      zeynep tufekci‏Verified account @zeynep 6 Apr 2021

      zeynep tufekci Retweeted Detroit Free Press

      Michigan has worst surge in the US, with rising hospitalizations & deaths. African-Americans, especially in Detroit, remain dramatically undervaccinated. Officials are begging for more vaccines. Meanwhile, @freep framing of ~1 in 10,000 breakthrough cases:https://twitter.com/freep/status/1379458652323639300 …

      zeynep tufekci added,

      Detroit Free PressVerified account @freep
      246 fully vaccinated Michiganders got COVID-19 between January and March, state reports http://rssfeeds.freep.com/~/648535138/0/freep/home~fully-vaccinated-Michiganders-got-COVID-between-January-and-March-state-reports/?utm_campaign=snd-autopilot …
      10:37 AM - 6 Apr 2021
      • 55 Retweets
      • 281 Likes
      • J. Norman Clifford Josh Patel David Sacks faggotini Con Murphy 💙 jd {{{ 𝘔𝘢𝘤_𝘝𝘢𝘶𝘨𝘩𝘢𝘯 }}} Zak
      12 replies 55 retweets 281 likes
        1. New conversation
        2. Thomas Paine  ✊‏ @TomPaineToday 6 Apr 2021
          Replying to @zeynep @freep

          what an irresponsible piece of journalism by @freep

          1 reply 0 retweets 12 likes
        3. Thomas Paine  ✊‏ @TomPaineToday 6 Apr 2021
          Replying to @TomPaineToday @zeynep @freep

          what a mindboggling absurd sentence.pic.twitter.com/w6q3VG2FT1

          2 replies 0 retweets 13 likes
        4. Show replies
        1. New conversation
        2. James O'Leary‏ @jpohhhh 6 Apr 2021
          Replying to @zeynep @freep

          These situations break my heart: there's no universal solution to balance the dual concerns of hiding info from the public thus becoming untrustworthy, and forcing people to read lengthy nuanced takes on every biomedical detail. We all deserve more empathy from each other

          1 reply 0 retweets 3 likes
        3. zeynep tufekci‏Verified account @zeynep 6 Apr 2021
          Replying to @jpohhhh @freep

          How about a headline that reflects reality?

          1 reply 0 retweets 59 likes
        4. Show replies
        1. New conversation
        2. intheaviary‏ @intheaviary 6 Apr 2021
          Replying to @zeynep @freep

          Is it possible that the death cases were vaccines that had been improperly handled or administered or something like that?

          1 reply 0 retweets 1 like
        3. Max Badrak‏ @maxbadrak 10 Apr 2021
          Replying to @intheaviary @zeynep @freep

          Out of 1.8 million vaccinated people a few will get sick. :(

          0 replies 0 retweets 1 like
        4. End of conversation
        1. someone random‏ @dajerseyboy 6 Apr 2021
          Replying to @zeynep @freep

          The article buries the fact that vaccines are not 100% effective and breakthroughs are rare halfway through the article. But everyone’s going to instead focus on the top-line number. That sucks.

          0 replies 0 retweets 8 likes
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        1. Mo Perry‏ @MoMoPerry 6 Apr 2021
          Replying to @zeynep @freep

          Unconscionable. Makes me 🤯

          0 replies 0 retweets 0 likes
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        1. Dr. M. Tullius "No Mercy for Seditionists" Cicero‏ @TulliusCicero43 6 Apr 2021
          Replying to @zeynep @freep

          oy

          0 replies 0 retweets 0 likes
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        1. Jayson DeMar‏ @jaysondemar 9 Apr 2021
          Replying to @zeynep @freep

          Oh no...they’ve done it againpic.twitter.com/xgwPI0mqII

          0 replies 0 retweets 2 likes
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