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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      More good news. Pfizer has the six month update. *Zero* hospitalizations among the vaccinated vs. 32 among the placebo group (n=46,307). Also real life data from South Africa, where B.1.351 is dominant: zero cases of COVID among the vaccinated vs. nine in the placebo (n=800).pic.twitter.com/2mLOh4LlRN

      232 replies 6,563 retweets 24,197 likes
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    2. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      There's so much consternation over vaccines losing efficacy or, worse, becoming useless against the variants. I'm not against worrying, and of course we should study this but keep in mind most of those results are lab studies that look at only a small part of the immune system.

      11 replies 135 retweets 1,258 likes
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    3. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      I've realized many have the incorrect mental model of the immune system: we conceive of it as a protective wall with a fixed height, and assume that vaccine efficacy represents that height. Wrong. I wrote a post explaining what trials do and don't measure. https://zeynep.substack.com/p/vaccine-efficacy-statistical-power …pic.twitter.com/zXKrWKUSLA

      8 replies 154 retweets 804 likes
      Show this thread
    4. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Do I want high efficacy numbers? Of course. But efficacy in trials only pertains to symptomatic COVID. Vaccines also work on other parts of the immune system that kick in only after infection takes hold (disease) but can prevent progression to severe disease and hospitalizations.

      3 replies 83 retweets 742 likes
      Show this thread
    5. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Why do trials measure symptomatic COVID and report that as efficacy? Faster, easier. Why do many studies measure parts of the immune system that prevent symptoms but not the rest? Same. That's why real life trial data > lab studies freaking everyone out. https://zeynep.substack.com/p/vaccine-efficacy-statistical-power …pic.twitter.com/WhTKkw6vsO

      4 replies 88 retweets 606 likes
      Show this thread
    6. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      I'm grateful to the scientists doing their job and worrying about, studying and developing boosters against variants. The rest of us should focus on vaccinating the world as fast as possible, and especially what more transmissible/severe variants mean for the *unvaccinated.*

      4 replies 102 retweets 772 likes
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    7. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Let me add: as vaccination scales to millions there will be some "breakthrough" cases—even few severe ones, especially among the elderly. Even common colds can cause deadly outbreaks in nursing homes. But every piece of real life data so far looks great. https://www.theatlantic.com/health/archive/2021/03/fourth-surge-variant-vaccine/618463/ …pic.twitter.com/k6L9BH4ulC

      6 replies 116 retweets 691 likes
      Show this thread
    8. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      Folks asking: We already know the two mRNA vaccines also overwhelmingly cut down any infection, including silent asymptomatic ones, *and* studies indicate even breakthrough disease after vaccination has lower viral load (hence likely less infectious). https://www.theatlantic.com/health/archive/2021/03/fourth-surge-variant-vaccine/618463/ …pic.twitter.com/EdWaVcmkxp

      6 replies 120 retweets 683 likes
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    9. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      zeynep tufekci Retweeted Rick

      Yeah. I constantly hear people invoke "immune evasion" (almost always a partial indication from studies that do not pertain to the whole immune system) as if it means vaccines becoming useless against variants. No! Anyway, let's vaccinate the world, ASAP.https://twitter.com/ricksterps/status/1379078510350860289 …

      zeynep tufekci added,

      Rick @ricksterps
      I wish we weren't allergic to good news involving covid. A lot of really positive data coming out recently. If I just read headlines I would believe the vaccines won't protect me from all the variants and they are only good for like 6 months. https://twitter.com/zeynep/status/1379064102824316929 …
      Show this thread
      15 replies 94 retweets 635 likes
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    10. zeynep tufekci‏Verified account @zeynep 5 Apr 2021

      zeynep tufekci Retweeted Nate Silver

      Let's put this here, but keep in mind: tens of millions in the US remain unvaccinated and are *just as much at risk* if infected (if not more, as some variants may also be more deadly). Vaccines are amazing, but the work is to vaccinate everyone, globally.https://twitter.com/NateSilver538/status/1379090275969216519 …

      zeynep tufekci added,

      Nate SilverVerified account @NateSilver538
      Just 222 COVID deaths reported in the US yesterday, which is the fewest since March 23, 2020. https://ourworldindata.org/covid-deaths  pic.twitter.com/FAyvg7tp4Z
      10 replies 111 retweets 589 likes
      Show this thread
      zeynep tufekci‏Verified account @zeynep 6 Apr 2021

      Flabbergasted at how much speculative worrying there is out there against current/future variants making our vaccines completely “ineffective” (I’ll easily take a bet against that) when the real issue is we have AMAZING vaccines that DO work, but not enough of them for the world!

      6:45 AM - 6 Apr 2021
      • 198 Retweets
      • 1,134 Likes
      • Niaz J. Norman Clifford Eric Schmidt 🌐🗽 A Josh Patel David Sacks yadda yadda etc. Con Murphy 💙
      41 replies 198 retweets 1,134 likes
        1. New conversation
        2. zeynep tufekci‏Verified account @zeynep 6 Apr 2021

          Common misleading headline/frame. Denominator is 1,800,000. That's ~1 in 10,000 breakthrough cases. Two, such cases are milder. Three, rare deaths, among the elderly happen at that scale. *Common colds* cause deadly outbreaks in nursing homes. And, only two were fully-vaccinated.pic.twitter.com/sCaNxh32xH

          7 replies 76 retweets 320 likes
          Show this thread
        3. zeynep tufekci‏Verified account @zeynep 6 Apr 2021

          zeynep tufekci Retweeted Detroit Free Press

          Michigan has worst surge in the US, with rising hospitalizations & deaths. African-Americans, especially in Detroit, remain dramatically undervaccinated. Officials are begging for more vaccines. Meanwhile, @freep framing of ~1 in 10,000 breakthrough cases:https://twitter.com/freep/status/1379458652323639300 …

          zeynep tufekci added,

          Detroit Free PressVerified account @freep
          246 fully vaccinated Michiganders got COVID-19 between January and March, state reports http://rssfeeds.freep.com/~/648535138/0/freep/home~fully-vaccinated-Michiganders-got-COVID-between-January-and-March-state-reports/?utm_campaign=snd-autopilot …
          12 replies 55 retweets 281 likes
          Show this thread
        4. End of conversation
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        2. Do the Right Thing‏ @TFDark 6 Apr 2021
          Replying to @zeynep @jbarro

          Chile seems like a good example of the ongoing danger of variants to the unvaccinated despite doing well in terms of vaccinating people.

          1 reply 0 retweets 2 likes
        3. zeynep tufekci‏Verified account @zeynep 6 Apr 2021
          Replying to @TFDark @jbarro

          No it does not, actually. Chile is too early in the process for us to tell if the P1 variant (may well be dominant there) has a differential impact compared with the wildtype for the vaccine it’s using, Sinovac, for which we have fairly little data to begin with.

          2 replies 0 retweets 8 likes
        4. Show replies
        1. New conversation
        2. Dr Ed‏ @notdred 6 Apr 2021
          Replying to @zeynep

          Hard to blame people for worrying given the alarmism that’s rampant in clickbait coverage and among some high-follower Twitter accounts...

          5 replies 4 retweets 68 likes
        3. zeynep tufekci‏Verified account @zeynep 6 Apr 2021
          Replying to @notdred

          I’m really at a loss what to do. Not blaming people. It’s in the news, it’s coming from (otherwise well-credentialed) experts. And seems the (many) who know better don’t openly pushback because parts of pandemic/expert social media has become so cliquish and hostile? Not sure.

          6 replies 5 retweets 72 likes
        4. Show replies
        1. Christina Yung‏ @cmyungtweet 6 Apr 2021
          Replying to @zeynep

          Christina Yung Retweeted relationships.txt

          I think some people just don't want to get vaccinated and are looking for excuses out. They don't care about the science. Like this guy, who doesn't believe in using dish soap:https://twitter.com/redditships/status/1378763864712609792 …

          Christina Yung added,

          relationships.txt @redditships
          Boyfriend refuses to use soap, grease abounds https://www.rareddit.com/r/relationship_advice/comments/mjituo … pic.twitter.com/4ZCIcKpgsv
          Show this thread
          1 reply 0 retweets 3 likes
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        1. Hao Ye‏ @Hao_and_Y 6 Apr 2021
          Replying to @zeynep

          I wonder how much of it is actually *general* vaccine hesitancy, and latching on to an explanation that still fits with a person's identity as otherwise supportive of public health.

          0 replies 0 retweets 3 likes
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