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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      zeynep tufekci Retweeted Isaac Bogoch

      WHO expert committee says delaying booster up to six weeks (given supply issues) rather than three is okay (based on existing data) and also says will update recommendations for delay as more data becomes available.https://twitter.com/BogochIsaac/status/1347545566679592960 …

      zeynep tufekci added,

      Isaac BogochVerified account @BogochIsaac
      Pfizer #COVID19 vaccine & new WHO recommendations: *You still need 2 doses *You should still try to dose as per schedule But due to supply, "interval between doses may be extended up to 42 days, on the basis of currently available clinical trial data". https://bit.ly/35jENK4 
      5 replies 32 retweets 85 likes
      Show this thread
    2. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      Details from the WHO expert committee: "Countries experiencing exceptional epidemiological circumstances may consider delaying for a short period the administration of the second dose as a pragmatic approach to maximizing the number of individuals benefiting from a first dose."pic.twitter.com/INAZ6Iy6j5

      4 replies 14 retweets 74 likes
      Show this thread
    3. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      Biden administration will indeed stop keeping second dose in reserve and front-load the vaccine distribution. (NB: I advocated for a *trial* asap on delayed booster & not keeping second dose in reserve. I also support having these trades-off discussions).https://www.cnn.com/2021/01/08/politics/biden-vaccine-strategy/index.html …

      7 replies 20 retweets 115 likes
      Show this thread
    4. zeynep tufekci‏Verified account @zeynep 22 Jan 2021

      zeynep tufekci Retweeted Michael Nedelman

      So update. CDC says some delay is okay & "if the second dose is administered beyond these intervals, there is no need to restart the series." I will repeat my plea that such modifications need a randomization and data gathering component for more clarity.https://twitter.com/MikeNedelman/status/1352406577664450561 …

      zeynep tufekci added,

      Michael NedelmanVerified account @MikeNedelman
      Amid doubts over Covid vaccine availability, CDC appears to have updated guidance Ppl can wait "up to 6 weeks" for 2nd dose if they can't make recommended interval Vaccines not interchangeable... but if you got Pfizer & it's no longer available, OK to get Moderna—or vice versa
      Show this thread
      7 replies 29 retweets 128 likes
      Show this thread
    5. zeynep tufekci‏Verified account @zeynep 24 Jan 2021

      zeynep tufekci Retweeted Martin Landray

      The man who leads the UK RECOVERY trials which produced incredibly useful information—including drugs that greatly reduce mortality—suggests a randomized trial of delayed dosing. Amazing how “controversies” evolve. 🤷‍♀️(Yes, we obviously should, as per first tweet in this thread.)https://twitter.com/MartinLandray/status/1353272270270181379 …

      zeynep tufekci added,

      Martin Landray @MartinLandray
      Looks like it’s time for a randomised trial of early vs later second dose. If start now, would have data to inform policy in Mar/Apr Might delay be better or worse? We don’t know. A large randomised trial would be very simple & very informative. https://www.theguardian.com/world/2021/jan/23/vaccine-experts-defend-uk-decision-to-delay-second-pfizer-covid-jab?CMP=Share_iOSApp_Other …
      4 replies 15 retweets 113 likes
      Show this thread
    6. zeynep tufekci‏Verified account @zeynep 12 Feb 2021

      Seems Michael Osterholm (of Biden Covid task force) calls for delaying the second dose a few months to increase coverage now. (Because I keep having to clarify: My co-authored piece called for *A TRIAL* exactly so such discussions could have better data). https://www.cidrap.umn.edu/covid-19/podcasts-webinars/episode-42 …pic.twitter.com/f1AkWZjIrv

      10 replies 8 retweets 69 likes
      Show this thread
    7. zeynep tufekci‏Verified account @zeynep 1 Apr 2021

      zeynep tufekci Retweeted Atul Gawande

      Updating this thread started on December 18, 2020 with me and @michaelmina_lab proposing an immediate *trial* for delaying the booster and monitoring the results. We both caught much grief then but if we had started a trial then, we'd know for sure by now.https://twitter.com/Atul_Gawande/status/1377275975050924040 …

      zeynep tufekci added,

      Atul GawandeVerified account @Atul_Gawande
      As cases and hospitalizations rise again, we can't count on behavior alone reversing this course. Therefore, it's time for the Biden admin to delay 2nd vax doses to 12 weeks. Getting as many people as possible a vax dose is now urgent. https://twitter.com/Atul_Gawande/status/1376888536129998850?s=20 …
      Show this thread
      16 replies 27 retweets 179 likes
      Show this thread
    8. Zoë McLaren, PhD‏ @ZoeMcLaren 3 Apr 2021
      Replying to @zeynep @michaelmina_lab

      CDC guidelines already allow for a 6 week delay in doses so we should be able to do that now without issue. I don’t think we need 12 week delays - we are vaccinating fast enough to get all second doses well before then especially if we hit up against hesitancy.

      2 replies 0 retweets 2 likes
    9. zeynep tufekci‏Verified account @zeynep 3 Apr 2021
      Replying to @ZoeMcLaren @michaelmina_lab

      I know but we've even been scheduling millions of people for *three week* intervals for Pfizer (almost certainly chosen to speed up trials since anything less than four weeks is essentially unprecedented in vaccine schedules—only exception I know is Japanese Encephalitis).

      3 replies 0 retweets 16 likes
    10. Nate Silver‏Verified account @NateSilver538 3 Apr 2021
      Replying to @zeynep @ZoeMcLaren @michaelmina_lab

      The state-run sites in NY automatically sign you up for a second Pfizer dose *exactly* three weeks (to the minute!) later. I guess they want to streamline things (and the state-run sites are quite efficient) but they don't even check to see if you have a conflict, etc.

      7 replies 1 retweet 31 likes
      zeynep tufekci‏Verified account @zeynep 3 Apr 2021
      Replying to @NateSilver538 @ZoeMcLaren @michaelmina_lab

      Yeah, many places are exactly like that. Even the CDC and the WHO—on the cautious side—say six weeks is okay (I'm putting aside everything else). I have not yet heard of a single reason beyond the obvious (speeding up trials) that the Pfizer has an unprecedentedly short interval.

      7:44 PM - 3 Apr 2021
      • 2 Retweets
      • 29 Likes
      • Bill hmpa Wendell "never been on 'Philadelphia'" Albright Bilbo Baggins Theme Arrow Elaine G Zoë McLaren, PhD
      3 replies 2 retweets 29 likes
        1. New conversation
        2. Zoë McLaren, PhD‏ @ZoeMcLaren 3 Apr 2021
          Replying to @zeynep @NateSilver538 @michaelmina_lab

          If both the CDC and WHO - extremely cautious orgs - say 6 weeks is fine if delay is “unavoidable”. Then shouldn’t it be a viable option now? It buys us ~2 weeks of extra first doses immediately. (If we’re willing to cancel and reschedule.) Would do a lot of good.

          3 replies 0 retweets 7 likes
        3. zeynep tufekci‏Verified account @zeynep 3 Apr 2021
          Replying to @ZoeMcLaren @NateSilver538 @michaelmina_lab

          I don't think they can reschedule existing ones (complicated) but since I called for *a trial* on all this back in December, I've talked with a large number of immunologists/vaccinologists with varying strong opinions on booster intervals. Not one said three weeks sounds ideal.

          5 replies 0 retweets 6 likes
        4. Show replies
        1. New conversation
        2. Zoë McLaren, PhD‏ @ZoeMcLaren 3 Apr 2021
          Replying to @zeynep @NateSilver538 @michaelmina_lab

          Trial intervals chosen for other reasons. If 3 weeks is “optimal” great. But we should be able to delay by a couple weeks and still get close to optimal. (Not an expert on that but the CDC and WHO seem ok with 6 weeks.)

          1 reply 0 retweets 0 likes
        3. Fyodor‏ @Fyodor32768 3 Apr 2021
          Replying to @ZoeMcLaren @zeynep and

          It's almost moot point now. Even if we canceled all the second doses and started doing only first doses tomorrow it would probably be too late to make an impact esp.with supply increasing. The time to have done it was January.

          1 reply 0 retweets 1 like
        4. Show replies
        1. New conversation
        2. Serkan‏ @emphimy 3 Apr 2021
          Replying to @zeynep @NateSilver538 and

          We are getting our first Pfizer shot tomorrow at Walgreens. They automatically scheduled second shot 28 days out.

          1 reply 0 retweets 1 like
        3. Information Junkie  👨‍💻‏ @JustTheFacts37 3 Apr 2021
          Replying to @emphimy @zeynep and

          Same here, had mine today. I assumed it was Moderna until they gave me the info for Pfizer

          0 replies 0 retweets 0 likes
        4. End of conversation

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