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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 3 Jan 2021

      I wrote this article (on New Years Eve!) because I was seeing so much media & even public health officials inappropriately reassure the public that the "new variant isn't more deadly." Technically correct but profoundly misleading about the real threat. https://www.theatlantic.com/science/archive/2020/12/virus-mutation-catastrophe/617531/ …pic.twitter.com/93Py6foXvO

      8 replies 37 retweets 143 likes
      Show this thread
    2. zeynep tufekci‏Verified account @zeynep 4 Jan 2021

      Another article advocating for an immediate trial for what happens when/if the booster is delayed, by @peterbachmd of Sloan-Kettering. He, too, suggests health-care workers as potential (could be others). "All breakthrough no follow-through" is costly. https://www.statnews.com/2021/01/04/stop-debating-first-shot-vs-set-aside-hospitals-should-compare-them/ …pic.twitter.com/XC2Mphm3gj

      4 replies 8 retweets 48 likes
      Show this thread
    3. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      zeynep tufekci Retweeted Isaac Bogoch

      WHO expert committee says delaying booster up to six weeks (given supply issues) rather than three is okay (based on existing data) and also says will update recommendations for delay as more data becomes available.https://twitter.com/BogochIsaac/status/1347545566679592960 …

      zeynep tufekci added,

      Isaac BogochVerified account @BogochIsaac
      Pfizer #COVID19 vaccine & new WHO recommendations: *You still need 2 doses *You should still try to dose as per schedule But due to supply, "interval between doses may be extended up to 42 days, on the basis of currently available clinical trial data". https://bit.ly/35jENK4 
      5 replies 32 retweets 85 likes
      Show this thread
    4. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      Details from the WHO expert committee: "Countries experiencing exceptional epidemiological circumstances may consider delaying for a short period the administration of the second dose as a pragmatic approach to maximizing the number of individuals benefiting from a first dose."pic.twitter.com/INAZ6Iy6j5

      4 replies 14 retweets 74 likes
      Show this thread
    5. zeynep tufekci‏Verified account @zeynep 8 Jan 2021

      Biden administration will indeed stop keeping second dose in reserve and front-load the vaccine distribution. (NB: I advocated for a *trial* asap on delayed booster & not keeping second dose in reserve. I also support having these trades-off discussions).https://www.cnn.com/2021/01/08/politics/biden-vaccine-strategy/index.html …

      7 replies 20 retweets 115 likes
      Show this thread
    6. zeynep tufekci‏Verified account @zeynep 22 Jan 2021

      zeynep tufekci Retweeted Michael Nedelman

      So update. CDC says some delay is okay & "if the second dose is administered beyond these intervals, there is no need to restart the series." I will repeat my plea that such modifications need a randomization and data gathering component for more clarity.https://twitter.com/MikeNedelman/status/1352406577664450561 …

      zeynep tufekci added,

      Michael NedelmanVerified account @MikeNedelman
      Amid doubts over Covid vaccine availability, CDC appears to have updated guidance Ppl can wait "up to 6 weeks" for 2nd dose if they can't make recommended interval Vaccines not interchangeable... but if you got Pfizer & it's no longer available, OK to get Moderna—or vice versa
      Show this thread
      7 replies 29 retweets 128 likes
      Show this thread
    7. zeynep tufekci‏Verified account @zeynep 24 Jan 2021

      zeynep tufekci Retweeted Martin Landray

      The man who leads the UK RECOVERY trials which produced incredibly useful information—including drugs that greatly reduce mortality—suggests a randomized trial of delayed dosing. Amazing how “controversies” evolve. 🤷‍♀️(Yes, we obviously should, as per first tweet in this thread.)https://twitter.com/MartinLandray/status/1353272270270181379 …

      zeynep tufekci added,

      Martin Landray @MartinLandray
      Looks like it’s time for a randomised trial of early vs later second dose. If start now, would have data to inform policy in Mar/Apr Might delay be better or worse? We don’t know. A large randomised trial would be very simple & very informative. https://www.theguardian.com/world/2021/jan/23/vaccine-experts-defend-uk-decision-to-delay-second-pfizer-covid-jab?CMP=Share_iOSApp_Other …
      4 replies 15 retweets 113 likes
      Show this thread
    8. zeynep tufekci‏Verified account @zeynep 12 Feb 2021

      Seems Michael Osterholm (of Biden Covid task force) calls for delaying the second dose a few months to increase coverage now. (Because I keep having to clarify: My co-authored piece called for *A TRIAL* exactly so such discussions could have better data). https://www.cidrap.umn.edu/covid-19/podcasts-webinars/episode-42 …pic.twitter.com/f1AkWZjIrv

      10 replies 8 retweets 69 likes
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    9. zeynep tufekci‏Verified account @zeynep 1 Apr 2021

      zeynep tufekci Retweeted Atul Gawande

      Updating this thread started on December 18, 2020 with me and @michaelmina_lab proposing an immediate *trial* for delaying the booster and monitoring the results. We both caught much grief then but if we had started a trial then, we'd know for sure by now.https://twitter.com/Atul_Gawande/status/1377275975050924040 …

      zeynep tufekci added,

      Atul GawandeVerified account @Atul_Gawande
      As cases and hospitalizations rise again, we can't count on behavior alone reversing this course. Therefore, it's time for the Biden admin to delay 2nd vax doses to 12 weeks. Getting as many people as possible a vax dose is now urgent. https://twitter.com/Atul_Gawande/status/1376888536129998850?s=20 …
      Show this thread
      16 replies 27 retweets 179 likes
      Show this thread
    10. Zoë McLaren, PhD‏ @ZoeMcLaren 3 Apr 2021
      Replying to @zeynep @michaelmina_lab

      CDC guidelines already allow for a 6 week delay in doses so we should be able to do that now without issue. I don’t think we need 12 week delays - we are vaccinating fast enough to get all second doses well before then especially if we hit up against hesitancy.

      2 replies 0 retweets 2 likes
      zeynep tufekci‏Verified account @zeynep 3 Apr 2021
      Replying to @ZoeMcLaren @michaelmina_lab

      I know but we've even been scheduling millions of people for *three week* intervals for Pfizer (almost certainly chosen to speed up trials since anything less than four weeks is essentially unprecedented in vaccine schedules—only exception I know is Japanese Encephalitis).

      7:25 PM - 3 Apr 2021
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      3 replies 0 retweets 16 likes
        1. Zoë McLaren, PhD‏ @ZoeMcLaren 3 Apr 2021
          Replying to @zeynep @michaelmina_lab

          With exponential growth every little change in R adds up and early action is key. We should push back timing to longest we can agree on immediately even as we debate the rest. It’s such a simple policy change but could be what gets R below 1. We can reverse later on.

          0 replies 0 retweets 1 like
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        2. Nate Silver‏Verified account @NateSilver538 3 Apr 2021
          Replying to @zeynep @ZoeMcLaren @michaelmina_lab

          The state-run sites in NY automatically sign you up for a second Pfizer dose *exactly* three weeks (to the minute!) later. I guess they want to streamline things (and the state-run sites are quite efficient) but they don't even check to see if you have a conflict, etc.

          7 replies 1 retweet 31 likes
        3. Cooper Vazao  🗽 💉‏ @CooperVazao 3 Apr 2021
          Replying to @NateSilver538 @zeynep and

          Yeah I actually would have liked to delay my 2nd vaccine and was surprised when I couldn't. I considered trying to see if I could change it but feared that would lead to that timeslot getting burned.

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. John O'Neil‏Verified account @THAToneil 3 Apr 2021
          Replying to @zeynep @ZoeMcLaren @michaelmina_lab

          So, who would decide this? FDA? CDC? White House?

          0 replies 0 retweets 0 likes
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