An NIH-led study plans to assess transmission after vaccination by asking college students to delay vaccination for four months. To me, this seems neither necessary nor ethically justifiable, and the study design probably can’t even answer their question.https://www.medpagetoday.com/infectiousdisease/covid19vaccine/91832 …
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I looked at the enrollment page, and it has not a word about the effects of delaying the vaccine. (It addresses “will the vaccine change my DNA” and “will it effect fertility”, but not... what if I do catch COVID during those four months, which is the point of the study).
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I’m definitely ok with using natural, unavoidable scarcities (like launching this in December when as college students were not going to be eligible soon) or discussing launching it someplace with no access to vaccines (though I am for vaccinating globally ASAP). But now? Here?
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Also, we already have a a lot of data on vaccines blunting transmission, and I am not even convinced this study (testing close-contacts of college students when a lot of spread happens in mass events like parties etc.) will give us anything more precise than what we already know.
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Replying to @zeynep
I'm not sure I agree on this part. There's a lot of data but I do think an RCT is much more informative. Observational studies are quite confounded by inequities in vaccination. This is separate from the ethics. (There are sometimes RCTs of flu vaccines in adults though.)
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What are we learning extra with this design?
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