Fuming. I supported a US trial of AstraZeneca so it could undo the *unnecessary* damage to vaccine confidence from their botched initial rollout. Yesterday, I was cautious because, again, press release, no data. Turns out AZ is botching this rollout, too.https://twitter.com/zeynep/status/1374060809144438785 …
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Yes. In my view, US institutions have generally been doing an excellent job with the vaccine trials. Credit/recognition where due.https://twitter.com/atlantictriangl/status/1374359120472649729 …
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The tragedy is this all could have been avoided if AstraZeneca waited 48 hours and released a paper along with their press release, and had not called essentially outdated results "interim" (they had newer results at hand!). Repeated unnecessary missteps damaging a good vaccine!
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This is how I feel. If it were available to me/my loved ones, I would not hesitate. The AZ vaccine itself is already delivering excellent results. But vaccination requires building confidence, not just good vaccines, and process matters. See Europe, too.https://twitter.com/ashishkjha/status/1374351260191649794 …
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I honestly do NOT think there's anything else wrong! The US Data and Safety Monitoring Board has the (more final) results, and it really doesn't look like there is anything wrong besides AZ's repeated errors in the public-facing handling of a good vaccine.https://twitter.com/pvancleaf/status/1374390973812252674 …
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Is there an explainer anywhere on this whole saga? Quite confusing trying to keep up as a non-specialist!
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I heard Oxford wanted to work with Merck but was forced by UK gov to work with AZ. Is that true? Also, how to we stop the irrational conspiracy theories that the US just doesn’t like the vaccine bc it’s inexpensive?
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Government responsibilities shouldn't be overlooked either. The UK govt reportedly pushed for a deal with AZ, a relatively inexperienced company with vaccines, instead of Merck, Oxford's usual partner, because AZ was willing to priorities delivery to UK and Merck wasn't.
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We all know Merck could've left us with zero vaccines, why on earth would we have taken such a risk?
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I’m biased cause I am going to work for AZ this fall, but this all seems really silly. If the data is good and consistent with their other trials why are we *that* angry that they put their best numbers in a press release? Seems like standard pharma behavior.
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my sister works in clinical trials, and last time we spoke about AZ's fucked up trials - months ago! - she was absolutely livid, on behalf of her entire profession. This was when they fucked up dose sizes between trial groups due to xenophobia
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