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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
      Replying to @kakape @zeynep

      So, I've suggested that we'll be chasing variants for a long time if we don't get SARCOV2 under control worldwide. I do find @zeynep's suggestion that the hippy-dippy rationale for global vaccination coverage is a strong(er) one. But a question for both of you...1/

      1 reply 5 retweets 23 likes
    2. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
      Replying to @gregggonsalves @kakape @zeynep

      Do you see transmission outside of places w/o good vaccination coverage as epidemiological neutral in a global sense? That is, we'll be able to cover "ourselves," boost against any variants, etc., but I am wondering if there is any biological downside to lack of access? 2/

      1 reply 2 retweets 13 likes
    3. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
      Replying to @gregggonsalves @kakape @zeynep

      I am fine making moral/ethical cases alone, but does unchecked spread in one region have any impact in another, more vaccinated locale? end/

      4 replies 2 retweets 15 likes
    4. zeynep tufekci‏Verified account @zeynep 16 Mar 2021
      Replying to @gregggonsalves @kakape

      It is, of course, better to have less of the virus anywhere. That said, a single chronic infection treated with antivirals is a completely plausible ongoing source for variants, and I do not need to tell you "HIV will mutate and drugs will stop working" wasn't what got access.

      1 reply 2 retweets 17 likes
    5. zeynep tufekci‏Verified account @zeynep 16 Mar 2021
      Replying to @zeynep @gregggonsalves @kakape

      In other words, it is not an implausible scenario that widespread vaccination plus boosters will do the job of protecting those in wealthy countries (immorally leaving behind everyone else) and also that variants do not arise solely because of unchecked population-level growth.

      1 reply 2 retweets 22 likes
    6. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
      Replying to @zeynep @kakape

      I am also interested in what @apoorva_nyc wrote about today. Will the immunosuppression related to untreated #HIV infection and #SARSCOV2 mean anything? Have no idea. But millions don't have access to ART still.

      1 reply 1 retweet 9 likes
    7. Apoorva Mandavilli‏Verified account @apoorva_nyc 16 Mar 2021
      Replying to @gregggonsalves @zeynep @kakape

      The more immunocompromised people, and just people generally, that are infected worldwide, the more evolution we will see. I don’t think it’s a poor scientific argument. We can only have boosters if the evolution is stepwise elsewhere and we know about it. No guarantee of either

      2 replies 2 retweets 34 likes
    8. Apoorva Mandavilli‏Verified account @apoorva_nyc 16 Mar 2021
      Replying to @apoorva_nyc @gregggonsalves and

      The boosters for previous variants may stop you from getting sick, but they’re not going to stop you from bringing the variant back into the country after travel. And then infecting immunocompromised/unvaccinated people over here.

      1 reply 2 retweets 19 likes
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    10. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
      Replying to @apoorva_nyc @zeynep and

      Ready to shame the world here along with @_HassanF @CarlosdelRio7 @jbkrell @MMKavanagh and many others.

      2 replies 1 retweet 36 likes
      zeynep tufekci‏Verified account @zeynep 16 Mar 2021
      Replying to @gregggonsalves @apoorva_nyc and

      That's what it may take, this time, too. As we've seen with HIV, too, it's perfectly plausible for effective drugs to shield a select few for a very, very long time—and the "but it will mutate elsewhere" never become realized as a big enough threat to move the needle.

      5:14 AM - 16 Mar 2021
      • 2 Retweets
      • 9 Likes
      • Timothy Lune Bethany Lilly Dr Ed Meredith (ALBlueDot) Céline Keller Thanas Goga Gregg Gonsalves Peter Staley Owen Blacker
      2 replies 2 retweets 9 likes
        1. New conversation
        2. Apoorva Mandavilli‏Verified account @apoorva_nyc 16 Mar 2021
          Replying to @zeynep @gregggonsalves and

          This is a different virus and a different mode of transmission. Fear of an airborne virus is very different from fear of hiv, which people (felt they) can control. It may take shame this time too, sure, but I think the scientific argument is absolutely valid

          1 reply 1 retweet 7 likes
        3. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
          Replying to @apoorva_nyc @zeynep and

          Also where did the variants that emerged in South Africa and Brazil originate from? Immunocompromised patients? I haven't been following so don't know.

          1 reply 0 retweets 1 like
        4. Show replies
        1. New conversation
        2. James Krellenstein‏ @jbkrell 16 Mar 2021
          Replying to @zeynep @gregggonsalves and

          I don’t think that is a proper analogy. In HIV, cART drugs suppress HIV replication by targeting various stages in the viral life cycle. So a large untreated population, which is not exposed to cART drugs, experiences no selective pressure to develop resistance mutations.

          5 replies 2 retweets 9 likes
        3. Gregg Gonsalves‏Verified account @gregggonsalves 16 Mar 2021
          Replying to @jbkrell @zeynep and

          No but millions of people unvaccinated just let stochastic mutations emerge too, which may simply hit the jackpot with resistance to vaccines, better transmissibility. etc.

          1 reply 0 retweets 1 like
        4. Show replies

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