A terrific take on what epidemiologists missed (understanding human responses and well-performed serological prevalence studies) and (and done well - vaccines) by @maciekboni
Well worth the read!https://theconversation.com/two-gaps-to-fill-for-the-2021-2022-winter-wave-of-covid-19-cases-156169 …
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Replying to @michaelmina_lab @maciekboni
While I do like the emphasis "take human behavior into account" in pandemic planning (that's my bread-and-butter! and duh!), I'm a little wary of being able to incorporate it into predictive modeling, though, for two reasons.
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First, modeling reflexivity (which is what social science folks call the thing being described here: people will respond to what's going on, which will change what's going on) in any way that's truly predictive is not just hard, may well be intractable in such situations.
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Two, this "must be behavior by elimination" a wee-bit dangerous. Could it be? Maybe. But it could also partly be things we don't—yet—understand. Did cases drop so precipitously in multiple countries with so many different cultures at the same time all due to behavior? I'm.. wary.pic.twitter.com/mslteOF6Pc
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Alternative: society is complex & interaction networks are power law distributed. Many highly connected nodes got infected/immune disrupting network transmission. *BUT* 1) that still means many ppl could still be susceptible, and 2) social networks change w time e.g. with seasons
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The question in the original article was why did epi models miss the relatively rapid, widespread drop? People all masked up/distanced in fear seems less plausible to me as the main explanatory variable given the magnitude, though I think it does matter somewhat.
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There is a “freak out threshold” when COVID-19 become the major cause of death, ~cancer & heart disease levels, the news media pays attention, lots of headlines, and there’s a broad increase in public health discipline. I had hoped the threshold would be much lower
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Of course. But I think that mattered less in winter 2021 because of the ideological polarization. Fear certainly has an influence but by January 2021, the interpretation of news was highly-fractured. But the drop is fairly uniform. I think there’s a puzzle there given magnitude.
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(I don’t have an answer if that’s not obvious).
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For sure, lots to learn. Hard to really capture the complexities of social networks in transmission models
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Yep.
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End of conversation
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