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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Eric Topol‏Verified account @EricTopol 21 Feb 2021

      The good news is that South Africa is back to its pre-B.1.351 baseline in covid cases. There's no proof this variant is more infectious. Its immune evasion is enough to explain how it took off. And the descent occurred without vaccines.pic.twitter.com/koLJn0iAFr

      145 replies 1,827 retweets 6,686 likes
    2. Nate Silver‏Verified account @NateSilver538 21 Feb 2021
      Replying to @EricTopol @notdred

      We know that B.1.351 causes some immune escape... but in your view does the rapid decline in cases in South Africa mean we should revise priors on just how much it has?

      8 replies 12 retweets 155 likes
    3. Eric Topol‏Verified account @EricTopol 21 Feb 2021
      Replying to @NateSilver538 @notdred

      Great question, w/ data so mixed: The failure of the Astra Zeneca vaccine to prevent mild-moderate infections The preserved, albeit reduced efficacy (cf ancestral) of Novavax (96->60) and J&J (72->57) The reinfections are concerning But perhaps not as bad as we've been thinking

      16 replies 44 retweets 304 likes
    4. zeynep tufekci‏Verified account @zeynep 21 Feb 2021
      Replying to @EricTopol @NateSilver538 @notdred

      Maybe a cautionary example of not extrapolating from small-n (confidence interval crossing zero, no indication about severe disease) or from in vitro studies of neutralizing antibodies to how the whole immune system will behave? I know *you* know and there was cause for concern+

      2 replies 2 retweets 34 likes
    5. zeynep tufekci‏Verified account @zeynep 21 Feb 2021
      Replying to @zeynep @EricTopol and

      ...and I think what SA did made sense, in terms of a precautionary step. Still, though, some of the reporting made it seem like the B.1.351 had, for sure, had complete immune escape rather than, hmm, concerning, let's 🧐🧐. (Again, I know you didn't but people were losing hope).

      2 replies 1 retweet 24 likes
    6. This Tweet is unavailable.
    7. zeynep tufekci‏Verified account @zeynep 21 Feb 2021
      Replying to @BRok_Horrible @EricTopol and

      I think a lot about what the public is hearing, I think I figured out a key problem there. Study: "it's not preventing mild/breakthrough disease". Public/journalist hears "Oh, it must be even weaker against severe disease!" Of course, that's not how it works because T cells etc.

      1 reply 0 retweets 18 likes
      zeynep tufekci‏Verified account @zeynep 21 Feb 2021
      Replying to @zeynep @BRok_Horrible and

      So if something is not stopping mild disease, the public/journalist interpretation can be that it's completely powerless against severe disease (because they think of it like height of a wall holding back a tide) rather than how the immune system works (layered/staged response).

      12:23 PM - 21 Feb 2021
      • 2 Retweets
      • 19 Likes
      • BlackHumor🏴🔥 χτύπα με με αυτό John Lee ntdisease Zina, Jewish Space Laser Paul Meyer Linn Marie Riccardo 💉💉💉 Fanciola Jasnah Kholin - 8964 - ACAB - 💉💉
      0 replies 2 retweets 19 likes
        1. This Tweet is unavailable.
        2. James Witker‏ @jwitker 21 Feb 2021
          Replying to @BRok_Horrible @zeynep and

          Yes, from following immunologists like Prof. Crotty, other experts like Dr. Monica Gandhi, it seems as though the protective cell-mediated immunity against variants is of key importance but not unacknowledged — or treated as theoretical — by media and opinionators.

          0 replies 0 retweets 1 like
        3. End of conversation

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