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zeynep tufekci
zeynep tufekci
zeynep tufekci
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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Aaron Richterman, MD‏ @AaronRichterman 12 Jan 2021

      5. Based on this, I think the possibility that these vaccines don't meaningfully reduce transmission (to the point that populations can move back towards normal life in due course) is low enough that we should treat this as a mostly theoretical concern at this point.

      1 reply 9 retweets 33 likes
      Show this thread
    2. Aaron Richterman, MD‏ @AaronRichterman 12 Jan 2021

      Aaron Richterman, MD Retweeted Aaron Richterman, MD

      6. An enduring lesson of this pandemic (& others) is the need to communicate uncertainty honestly (in both directions). Of course its reasonable to be careful, but lets not forget that this theoretical concern is being cited as a reason not to get the vaxhttps://twitter.com/AaronRichterman/status/1348494121019826178?s=20 …

      Aaron Richterman, MD added,

      Aaron Richterman, MD @AaronRichterman
      Returning to normal activities is one important motivator for public to get vaccinated. Emphasizing that vaccines are unlikely to facilitate this because lots of transmission might happen anyway undermines this, especially when that seems unlikely based on what we know now 👇🏻 https://twitter.com/MonicaGandhi9/status/1347988651179798530 …
      Show this thread
      2 replies 6 retweets 31 likes
      Show this thread
    3. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      Aaron Richterman, MD Retweeted Eric Meyerowitz, MD

      7. implications of monoclonal post-exposure prophylaxis data on transmissionhttps://twitter.com/EricMeyerowitz/status/1354231883190722571?s=20 …

      Aaron Richterman, MD added,

      Eric Meyerowitz, MD @EricMeyerowitz
      1/ Key question right now is how much SARS-CoV-2 vaccines will decrease transmission. Data from Regeneron mAb cocktail prevention press release may help us think about this https://investor.regeneron.com/news-releases/news-release-details/regeneron-reports-positive-interim-data-regen-covtm-antibody …
      Show this thread
      1 reply 0 retweets 7 likes
      Show this thread
    4. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      Aaron Richterman, MD Retweeted Aaron Richterman, MD

      8. More on why reducing symptoms/severity w vaccines will probably reduce transmissionhttps://twitter.com/AaronRichterman/status/1351548094710652928?s=20 …

      Aaron Richterman, MD added,

      Aaron Richterman, MD @AaronRichterman
      These two statements are at first confusing, but crucial to understanding prevention of cov2 transmission, including through use of vaccines. https://twitter.com/BogochIsaac/status/1351544832771186691 …
      Show this thread
      1 reply 1 retweet 8 likes
      Show this thread
    5. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      8a. (Aside - Good paper with biases to be mindful of when comparing secondary attack rates of symptom/asymptomatic in households (page 19). h/t @mugecevik) https://dash.harvard.edu/handle/1/37366192 …pic.twitter.com/ez5IssUk0F

      1 reply 0 retweets 6 likes
      Show this thread
    6. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      Aaron Richterman, MD Retweeted Aaron Richterman, MD

      9. Some more discussion on Moderna dose 2 testinghttps://twitter.com/AaronRichterman/status/1350591945702318083 …

      Aaron Richterman, MD added,

      Aaron Richterman, MD @AaronRichterman
      Here is one more look at Supplementary Table 18 from the Moderna NEJM paper, the best direct data we have on this question. Follow me here for a moment 🧵 /1 https://twitter.com/zeynep/status/1350586029359702016?s=20 … pic.twitter.com/7ID8Tjlq0u
      Show this thread
      1 reply 0 retweets 4 likes
      Show this thread
    7. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      Aaron Richterman, MD Retweeted

      10. Implications from regular pcr monitoring after natural infection. Less infections, lower viral load, more asymptomatic. Will reduce transmission. https://twitter.com/dylanhmorris/status/1357003968208121861 …

      Aaron Richterman, MD added,

      This Tweet is unavailable.
      1 reply 0 retweets 8 likes
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    8. Aaron Richterman, MD‏ @AaronRichterman 3 Feb 2021

      Aaron Richterman, MD Retweeted Aaron Richterman, MD

      10a. That said, similar caveats as below re whether those were even all reinfections.https://twitter.com/AaronRichterman/status/1355567294882131972 …

      Aaron Richterman, MD added,

      Aaron Richterman, MD @AaronRichterman
      Important thread below on immunologic basis for skepticism of 0% protection by prior natural infection on reinfection with B1.351 suggested by the small novavax study in S Africa So why else might they have found identical cases by sero+/-? Speculation before seeing full data: https://twitter.com/profshanecrotty/status/1355552010158764036 …
      Show this thread
      1 reply 0 retweets 5 likes
      Show this thread
    9. Aaron Richterman, MD‏ @AaronRichterman 6 Feb 2021

      11. More data from the Oxford/az randomized clinical trial. Vaccinated ppl who developed infection had lower viral loads and were pcr+ for one week shorter time relative to placebo. True for both asymptomatic and symptomatic cases. =>reduced transmission https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3779160 …pic.twitter.com/NsnUzCmrZk

      2 replies 3 retweets 16 likes
      Show this thread
    10. Aaron Richterman, MD‏ @AaronRichterman 8 Feb 2021

      Aaron Richterman, MD Retweeted Yaniv Erlich

      12a. And real world data from Israel. Interesting analysis inferring vaccine status by age and following cycle thresholds over time, suggesting lower VL in vaccinees w infection. Cool time series. Caveat: unclear what symptom status is but assume mostly symptom prompted testing.https://twitter.com/erlichya/status/1358477762495930368 …

      Aaron Richterman, MD added,

      Yaniv Erlich @erlichya
      Idea💡: we know the age of the person and the date of the test. Since vaccination was started with 60+, we can compare the average Ct value positives in this age group as a function of time and compare to 40-60 as a control. Here are the results: [Red: 60+;Blue:40-60] pic.twitter.com/X24YG5SCmZ
      Show this thread
      2 replies 1 retweet 5 likes
      Show this thread
      zeynep tufekci‏Verified account @zeynep 8 Feb 2021
      Replying to @AaronRichterman

      zeynep tufekci Retweeted Roy Kishony

      Similar Ct comparison (preprint not out yet).https://twitter.com/RoyKishony/status/1358695273468469250 …

      zeynep tufekci added,

      Roy Kishony @RoyKishony
      Reduced viral loads 12 days following Pfizer-BioNTech #COVID19 vaccine. medRxiv (to appear soon). with @idanyelin @MatanLevine in collaboration with #MaccabiTech; @TechnionLive pic.twitter.com/T3Yqdl71y4
      6:23 AM - 8 Feb 2021
      • 2 Likes
      • Deirdre Connolly¹ Aaron Richterman, MD
      1 reply 0 retweets 2 likes
        1. AstroBear‏ @mugsymugsy18 8 Feb 2021
          Replying to @zeynep @AaronRichterman

          Is this the preprint?https://www.medrxiv.org/content/10.1101/2021.02.06.21251283v1 …

          0 replies 0 retweets 2 likes
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