We need to think harder the takeaway from the trials, as well as reporting on the variants and Nab titers etc. For the virology and immunology people, of course those details matter as they plot the (future) boosters. For the rest of us, the really key question is disease burden.
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Yes. These vaccines are all home runs. Incredible fast home runs. Going by the trials (and taking trial date/place/size into account), I'm not sure there are consequential differences in their effectiveness—i.e. results in the world. We just need more. https://twitter.com/BRok_Horrible/status/1356748390734966786 …
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Let me put it this way. If we started random-blind vaccinating large groups (without anyone knowing what they got), I wouldn't be surprised that if, in a year, we wouldn't be able to easily tell which group was which if they were matched in timing/booster/vax period.
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I gotta finish a piece (*waves at editor*) but if I can match the symptoms across trials, I'll see if I can do a power calculation for the size of the trial group to be able to tell the differences between different vaccines through disease burden. They're all that good.
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Wow, not even one?
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Not a single one. And the only "severe" one in Pfizer, for example, is someone who had 93% oxygen saturation. She didn't need any medical care. One more percent, and she wouldn't even be considered "severe".
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The problem is that general public apprehension and restrictions are driven by cases, not hospitalization
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The cases are going down dramatically both in numbers and very much in severity in all the trials as well.
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Do you have the data by age group? Without that, don't know what to make of the numbers.
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Thank you for sharing. I think we all needed some good news and need to look at life in an optimistic manner rather than Pessimism.
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