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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Joseph Allen‏ @j_g_allen 1 Feb 2021

      More adding support for delayed 2nd dose strategy. @mtosterholm + @mlipsitch are supportive. Early calls to consider this (notably op-ed by @michaelmina_lab + @zeynep in mid-Dec) were too quickly dismissed by some, IMO. It's a race against new variants.https://www.cidrap.umn.edu/news-perspective/2021/02/experts-tout-delaying-2nd-covid-vaccine-dose-us-deaths-mount …

      11 replies 32 retweets 107 likes
    2. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @j_g_allen @mtosterholm and

      Dismissed, heh. Got a lot of "how dare you", too. If we had started then—randomizing among those who'd already had a single shot in trials and also after the EUA—we'd have a lot more data-driven clarity now on how best to proceed.

      2 replies 1 retweet 26 likes
    3. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @zeynep @j_g_allen and

      I remain worried that this is happening either by overly-broad strategy (everyone is delayed equally, UK) or by fiat (not putting enough effort into tracking people for boosters) and may disproportionately impact the elderly—who probably have less leeway.

      1 reply 1 retweet 9 likes
    4. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @zeynep @j_g_allen and

      (Also is three weeks too short for a robust response? It increasingly seems that non-standard interval was chosen mostly to speed up trials. Randomizing three weeks and, say, five or six weeks and comparing outcomes might be useful and seems pretty low risk?).

      3 replies 2 retweets 18 likes
    5. Michael Mina‏Verified account @michaelmina_lab 1 Feb 2021
      Replying to @zeynep @j_g_allen and

      Very low risk. The immune system isn’t going to drop off a cliff at 28 days. Nor at 45 or 60 days.

      4 replies 1 retweet 22 likes
    6. Josh Barocas, MD‏ @jabarocas 1 Feb 2021
      Replying to @michaelmina_lab @zeynep and

      So, immunologically speaking, I don't disagree. But if we are going to change the recommendation (1 dose, delayed 2nd, etc)-then we are going to have a lot of ppl who mistrust us even more. We've asked ppl to follow the science/evidence. We've asked ppl to trust us (scientists)..

      2 replies 0 retweets 4 likes
    7. Josh Barocas, MD‏ @jabarocas 1 Feb 2021
      Replying to @jabarocas @michaelmina_lab and

      While we think that the vaccine will be effective w/delayed dose, there's no hard evidence. We're swimming upstream against a river of mistrust already. For those of us on the ground, having the conversations, this is a hard sell. IMO.

      1 reply 0 retweets 4 likes
    8. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @jabarocas @michaelmina_lab and

      On the first, Michael and I had asked for a trial of delaying the dose back in December partially because I am indeed very attuned to the question of trust. Even though delaying doses is not uncommon, even a request to collect data was treated as a no-go. So a few things on that.

      3 replies 0 retweets 2 likes
    9. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @zeynep @jabarocas and

      Insisting that the only scientific way was whatever the initial trial happened to be—which isn't a practice set in stone, is modified routinely for other vaccines, and given the emergency we face, def something to discuss—kind of became an own-goal, I think. So now it's harder. +

      1 reply 0 retweets 2 likes
      zeynep tufekci‏Verified account @zeynep 1 Feb 2021
      Replying to @zeynep @jabarocas and

      Meanwhile, both WHO and CDC have said six weeks is okay but we can't even do that, partly because of that unnecessarily rigid messaging. We could have had better data, we don't. UK could have had a more targeted approach, they don't.

      5:53 PM - 1 Feb 2021
      • 1 Like
      • Josh Barocas, MD
      2 replies 0 retweets 1 like
        1. Josh Barocas, MD‏ @jabarocas 1 Feb 2021
          Replying to @zeynep @michaelmina_lab and

          Exactly—unnecessarily rigid messaging but also a completely disjointed messaging.

          0 replies 0 retweets 1 like
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        2. zeynep tufekci‏Verified account @zeynep 1 Feb 2021
          Replying to @zeynep @jabarocas and

          If one had two children, and these vaccines and a shortage, is the answer to vaccinate only one, prime & booster three weeks apart, and leave the other completely unvaccinated, or vaccinate both if they get the booster six weeks later? We wanted data because that is our question.

          1 reply 0 retweets 2 likes
        3. Josh Barocas, MD‏ @jabarocas 1 Feb 2021
          Replying to @zeynep @michaelmina_lab and

          And we squandered a prime opportunity to answer that and now are left making best guesstimates and asking ppl to trust us (when many of those ppl we’ve (med establishment) f-Ed over in the past too many times to count.

          1 reply 0 retweets 0 likes
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