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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Prof. Akiko Iwasaki‏Verified account @VirusesImmunity 10 Jan 2021

      What is the relevance of viral load in #COVID19 disease severity? A very talented @YaleMSTP student @SilvaJ_C found that saliva viral load to be a better predictor of disease than nasopharyngeal viral load. Here is a thread to explain the findings. (1/n)https://www.medrxiv.org/content/10.1101/2021.01.04.21249236v1 …

      71 replies 1,259 retweets 2,782 likes
      Show this thread
    2. Prof. Akiko Iwasaki‏Verified account @VirusesImmunity 10 Jan 2021

      I preface by saying that numerous fantastic studies by many have demonstrated nasopharyngeal viral load to correlate with disease severity and mortality, while others do not find such correlation. Here are some of these studies. (2/n)pic.twitter.com/XyunWFP0Bp

      4 replies 37 retweets 183 likes
      Show this thread
    3. Prof. Akiko Iwasaki‏Verified account @VirusesImmunity 10 Jan 2021

      Being at @yale, the birthplace of #SalivaDirect and everything saliva bc of awesome colleagues like @awyllie13 @NathanGrubaugh @VogelsChantal et al, we had access to both saliva and nasopharyngeal (NP) samples from the same patients to do direct comparisons. (3/n)

      2 replies 20 retweets 185 likes
      Show this thread
    4. Gisela Wilson, PhD‏ @GiselaFWilson 23 Jan 2021
      Replying to @VirusesImmunity @Yale and

      Having now visited two saliva-based testing sites, I’m concerned how long lines and the need for maskless sample collection and related factors will play out considering a ~ 7.6x increase in transmissibility

      2 replies 0 retweets 0 likes
    5. Anne Wyllie‏ @awyllie13 23 Jan 2021
      Replying to @GiselaFWilson @VirusesImmunity and

      Saliva can be pooled in the mouth before removing the mask and deposited into a tube. A mask still needs to be removed for swab collection. We-and others-are also finding it hard to culture virus from saliva, so it may pose less of a risk than aerosols/other respiratory droplets.

      1 reply 0 retweets 0 likes
    6. Gisela Wilson, PhD‏ @GiselaFWilson 23 Jan 2021
      Replying to @awyllie13 @VirusesImmunity and

      At the collection site I visited, people are maskless. Swab collection can be performed via drive through sites. Though, come to think of it, saliva sample collection could too — just not way these testing sites are being set up.

      2 replies 0 retweets 0 likes
    7. Gisela Wilson, PhD‏ @GiselaFWilson 23 Jan 2021
      Replying to @GiselaFWilson @awyllie13 and

      Also spacing is 6ft, with @AdamJKucharski ‘s B117 ⬆️ transmissibility estimate of 7.6x, increase in social distancing should 6x7.6 = 45ft, especially maskless. [I’m not including duration of exposure or ventilation properties of the rooms as possible mitigation variables.]

      2 replies 0 retweets 1 like
      zeynep tufekci‏Verified account @zeynep 23 Jan 2021
      Replying to @GiselaFWilson @awyllie13 and

      I don't know of any reason to assume that transmissibility increase estimates translate linearly distance guidelines and I'd really recommend against doing such calculations.

      8:11 AM - 23 Jan 2021
      1 reply 0 retweets 0 likes
        1. New conversation
        2. Gisela Wilson, PhD‏ @GiselaFWilson 23 Jan 2021
          Replying to @zeynep @awyllie13 and

          What calculations do you recommend as Universities set up their saliva-based testing sites based on old (pre-B117) assumptions?

          1 reply 0 retweets 0 likes
        3. Gisela Wilson, PhD‏ @GiselaFWilson 23 Jan 2021
          Replying to @GiselaFWilson @zeynep and

          If you want to stay away from numbers and approximations, another way to say this is that the ‘holes’ of the swiss cheese model of prevention are potentially a lot larger.

          0 replies 0 retweets 0 likes
        4. End of conversation

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