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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 4 Jan 2021

      Ashish K. Jha, MD, MPH Retweeted Robert Wiblin

      An excellent thread on epistemology What do we know and how do we know it? A narrow view of what we know, what is data can lead us into mental traps This is not about delayed vs immediate vaccine doses This is about what do we mean when we say, follow the science. H/T @zeynephttps://twitter.com/robertwiblin/status/1345800480144945152 …

      Ashish K. Jha, MD, MPH added,

      Robert Wiblin @robertwiblin
      A serious reasoning error that is particularly common among educated people is to argue that if a study hasn't been done on a particular question we have 'no data', and therefore no basis on which to form beliefs or act. This is incorrect and dangerous. 1/
      Show this thread
      15 replies 58 retweets 184 likes
    2. zeynep tufekci‏Verified account @zeynep 4 Jan 2021
      Replying to @ashishkjha

      And thank you for being out there with reasoned discussion on this obviously thorny, complex topic. It's much easier to stay quiet or to advocate for what appears bureaucratically safe rather than dive into discussions of trade-off in the face of uncertainty and a dire situation.

      3 replies 2 retweets 28 likes
    3. Gregg Gonsalves‏Verified account @gregggonsalves 4 Jan 2021
      Replying to @zeynep @ashishkjha

      We've all been diving into these trade-offs, even if we think a shift from a regimen with documented, robust efficacy to one with less certain effects is unwise. Juxtaposing it as "reasoned discussion" vs "bureaucratic safety" is your own value judgment coming into play here.

      1 reply 0 retweets 20 likes
      zeynep tufekci‏Verified account @zeynep 4 Jan 2021
      Replying to @gregggonsalves @ashishkjha

      There *has* been a lot of bureaucratic safetyism—not just talking about the vaccine debate—but obviously that doesn't mean everyone I disagree with is doing that. (Moreover, in this case I don't even have the basis to defend strong opinion on either side).

      7:42 AM - 4 Jan 2021
      • 8 Likes
      • John Q Public Vineet Tiruvadi Walt Axson Jeneen Interlandi Dave Kasten arm and hammer and dance Michael Bishop 🇨🇦🇺🇸
      3 replies 0 retweets 8 likes
        1. New conversation
        2. Gregg Gonsalves‏Verified account @gregggonsalves 4 Jan 2021
          Replying to @zeynep @ashishkjha

          OK, sorry I misread the response in this case.

          2 replies 0 retweets 3 likes
        3. zeynep tufekci‏Verified account @zeynep 4 Jan 2021
          Replying to @gregggonsalves @ashishkjha

          No problem. It's pretty clear that there are reasoned arguments for and against any schedule changes, though it may well be that it doesn't matter anyway because we are so slow. But important to watch what happens in UK, which should give us more information.

          1 reply 0 retweets 0 likes
        4. Show replies
        1. New conversation
        2. zeynep tufekci‏Verified account @zeynep 4 Jan 2021
          Replying to @zeynep @gregggonsalves @ashishkjha

          In my case, when we wrote an op-ed calling for a *trial*—just a trial—for a later dose to increase coverage, we did get many people saying we had no data to call for even a trial, how dare we call for changing the protocol from a phase III trial. Not you. But it was widespread.

          1 reply 0 retweets 6 likes
        3. Gregg Gonsalves‏Verified account @gregggonsalves 4 Jan 2021
          Replying to @zeynep @ashishkjha

          I am a big proponent of phase IV studies--phase III should never be the be-all/end-all. But I wish we had as much enthusiasm about solving delivery, production problems as we have for stretching out the meagre supplies we have now as a temporary stop-gap.

          1 reply 1 retweet 15 likes
        4. Show replies
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        2. Gregg Gonsalves‏Verified account @gregggonsalves 4 Jan 2021
          Replying to @zeynep @ashishkjha

          And sorry but the epistemology stuff is slightly annoying. We've had three decades of assault on the regulatory state pushing for less evidence for public policies, particularly at FDA, eroding evidence base, while we pay higher prices than ever for what we get. 1/

          1 reply 1 retweet 11 likes
        3. Gregg Gonsalves‏Verified account @gregggonsalves 4 Jan 2021
          Replying to @gregggonsalves @zeynep @ashishkjha

          And the call: rely on real world evidence, other kinds of data, personalized medicine, because RCTs are the 20th century's tool. The same logic applies: people are dying we have to move more quickly, trade answers for access. 2/

          1 reply 0 retweets 8 likes
        4. Show replies

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