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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Florian Krammer‏Verified account @florian_krammer 3 Jan 2021

      1) If we want to generate difficult viral escape mutants in the lab (e.g. for epitope mapping), we subject the virus to low antibody pressure and then slowly move up. A little bit like after one vaccine dose. I think it would be good to give the second dose as soon as possible.

      146 replies 2,103 retweets 5,875 likes
      Show this thread
    2. Alex Merz‏ @Merz 3 Jan 2021
      Replying to @florian_krammer

      @zeynep

      1 reply 0 retweets 5 likes
    3. zeynep tufekci‏Verified account @zeynep 3 Jan 2021
      Replying to @Merz @florian_krammer

      Great to hear Florian thinks 12 weeks isn't a big problem—which I heard from many in the field which, as I said, I am not in a position to judge but the number of experts saying that is reassuring. I think everyone agrees boosters as soon as possible is a good idea.

      11 replies 4 retweets 63 likes
    4. George Bon Jovi Washington‏ @JasonRussell1 3 Jan 2021
      Replying to @zeynep @Merz @florian_krammer

      That is absolutely not what he said. Re-read his comments above. He says he does not KNOW that it will be a big problem but immediately says “minimize the interval”

      1 reply 0 retweets 36 likes
    5. zeynep tufekci‏Verified account @zeynep 3 Jan 2021
      Replying to @JasonRussell1 @Merz @florian_krammer

      I am not and I cannot argue with Florian! Not my area at all! There are immunologists who think other things on this. I'm just pointing out that I haven't encountered anyone who doesn't think we shouldn't "minimize the interval."

      2 replies 1 retweet 6 likes
    6. Alex Merz‏ @Merz 3 Jan 2021
      Replying to @zeynep @JasonRussell1 @florian_krammer

      Are there? Immunologists who have studied viral evolution and escape?

      1 reply 0 retweets 2 likes
    7. zeynep tufekci‏Verified account @zeynep 3 Jan 2021
      Replying to @Merz @JasonRussell1 @florian_krammer

      zeynep tufekci Retweeted Sarah Cobey

      Alex, you keep wanting me to do a survey and neither of us seems to have one. I obviously cannot judge something like this which has top-notch actual experts disagreeing! You really should ask people like Klugman or Iwasaki or her below or others.https://twitter.com/sarahcobey/status/1345094869652537351 …

      zeynep tufekci added,

      Sarah Cobey @sarahcobey
      Replying to @sarahcobey @LauringLab and 8 others
      Overall, I completely agree with @jbloom_lab that managing viral evolution is a higher order problem that we eventually need to investigate, but there's no reason it should slow efforts to vaccinate now. Stronger and broader immunity now will only help.
      1 reply 1 retweet 5 likes
    8. Alex Merz‏ @Merz 3 Jan 2021
      Replying to @zeynep @JasonRussell1 @florian_krammer

      What that entire thread — with many outstanding scientists — says is, "we don't know."

      1 reply 0 retweets 6 likes
      zeynep tufekci‏Verified account @zeynep 3 Jan 2021
      Replying to @Merz @JasonRussell1 @florian_krammer

      With some of them coming strongly on the side of delaying the booster, some not. On repeat: you should ask people like Klugman or Iwasaki (actual experts) among many, not me! I can only say that there are trade-offs on all sides, a sucky situation & credentials on both sides.

      10:49 AM - 3 Jan 2021
      • 7 Likes
      • Chris Mooiweer Metasequoia Rachel Kann Jermaine Heath LaLu poleiro de pombo contra o #PL490 Brian Chu
      1 reply 0 retweets 7 likes
        1. New conversation
        2. Alex Merz‏ @Merz 3 Jan 2021
          Replying to @zeynep @JasonRussell1 @florian_krammer

          No one on that thread is "coming strongly on the side of delaying the booster."

          1 reply 0 retweets 4 likes
        3. Name‏ @Name52274187 4 Jan 2021
          Replying to @Merz @zeynep and

          I believe @VirusesImmunity

          1 reply 0 retweets 0 likes
        4. Show replies

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