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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      If rich countries can do with less, supply (of other vaccines) for poorer countries will be more. I didn't say there was an excess now because there's clearly a shortage now *everywhere*, and hence the painful discussions of trade-offs, but it's pretty straightforward.

      1 reply 0 retweets 0 likes
    2. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      Again, I think you're overly optimistic about liquidity in the vaccine market.

      1 reply 0 retweets 0 likes
    3. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Not the way things are, you are right. But the way things are is pretty terrible. I'm pointing out that equity is not at all on one side of the trade-off debate. Ideally, yeah, we increase the supply of stable/easier one-dose vaccines and do away with the trade-off. Of course.

      2 replies 0 retweets 1 like
    4. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @zeynep @Merz @halvorz

      Also, even in the US, where we'll probably stick to the booster schedule (though do you know why three weeks instead of four to six except to have sped up the Pfizer trial?) there'll be many who miss booster we should collect data.

      1 reply 0 retweets 2 likes
    5. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      Absolutely.

      1 reply 0 retweets 0 likes
    6. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep @halvorz

      Many MANY opportunities for high quality longitudinal and cohort work here.

      1 reply 0 retweets 1 like
    7. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Yes. And also, again, without judgment on the outcome of this question, there have been a bunch of curveballs from trials that prior knowledge did not predict. Efficacy of mRNA vaccines. Dexamethasone (many thought it would not work and would harm) that emerged from UK/RECOVERY.

      1 reply 0 retweets 0 likes
    8. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @zeynep @Merz @halvorz

      Ideally, UK would do this as if it were an adaptive trial: with transparency and a means to halt/reverse (especially for those at high risk for severe disease). Or do a tiered approach: emphasize booster for elderly while watching younger cohorts. Etc.

      1 reply 0 retweets 2 likes
    9. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @zeynep @Merz @halvorz

      I think trade-offs and some kitchen-sinking is inevitable, and ideally we'd approach this with "how do we resolve this as fast as possible, while maintaining public trust" kind of approach. To me, that's always randomize when/if possible, collect data always.

      1 reply 0 retweets 2 likes
    10. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @zeynep @Merz @halvorz

      zeynep tufekci Retweeted Keith Klugman

      (Speaking of Gates Foundation. Forgot to mention. Here’s Klugman of Gates, who needs no introduction about his credentials and experience with vaccines and vaccination.)https://twitter.com/findingpneumo/status/1339556859473227778 …

      zeynep tufekci added,

      Keith Klugman @findingpneumo
      First doses of Pfizer/Moderna vaccines are 90%+ effective after 14 days. Most high risk lives will be saved by giving all these limited early supplies of vaccine as first doses - second doses can be given later if first dose effectiveness wanes or when supply improves
      1 reply 2 retweets 3 likes
      zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @zeynep @Merz @halvorz

      zeynep tufekci Retweeted Keith Klugman

      And Klugman’s response to UK’s decision. (My sense is people like him, with deep global experience and working with vulnerable populations, are a lot more experienced with such thorny trade-offs which are newer to experts from wealthy countries of great privilege).https://twitter.com/findingpneumo/status/1344268340857081858 …

      zeynep tufekci added,

      Keith Klugman @findingpneumo
      Way to go UK vaccine advisory committee - 1st doses protect more people using the three EUA vaccines in US or UK than do 2nd doses - limited supply in US allows excess deaths by restricting first doses of covid vaccines - 2nd doses are still valuable but can and should be delayed https://twitter.com/PeterHorby/status/1344190491781443585 …
      4:12 PM - 2 Jan 2021
      • 1 Like
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      0 replies 0 retweets 1 like

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