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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep @halvorz

      And there's also the issue that participants were consented for the trials-as-conducted. A change in design as you suggest would have required that everyone be re-consented.

      1 reply 0 retweets 2 likes
    2. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Yeah, I realize we were surprised with mRNA-vax efficacy. I totally remember the April-June headlines and predictions. I realize why we did the trials the way we did. It's just that given the terrible price of the shortages, we should have adapted the trials as fast as possible.

      1 reply 0 retweets 2 likes
    3. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      The doses are being manufactured considerably faster than they're being adminstered.

      2 replies 0 retweets 3 likes
    4. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      We have even bigger screwups, sure. For the moment. Maybe we'll manage to get stuck here. But that's not relevant to the UK booster spacing issue, and also doesn't make the shortage problem, or the deep global inequity, go away.

      1 reply 0 retweets 1 like
    5. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      What will attenuate that inequity is not stretching current stocks further. No one seriously believes that if we had say 40% more available Moderna vaccine, that *any* of it would end up in lower-income countries.

      1 reply 0 retweets 1 like
    6. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep @halvorz

      What will attenuate the inequity? Inexpensive, highly stable, safe, effective vaccines.

      1 reply 0 retweets 1 like
    7. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      One, at least Moderna is absolutely within the capability of many, many LMIC. (Pfizer/BioNTech, not so much). Two, if rich countries stretch Moderna/Pfizer more, that's a lot more of the rest for LMIC. Doesn't resolve question but equity side has that to consider.

      2 replies 0 retweets 0 likes
    8. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      I don't buy that for a moment. Moderna is already well behind their production targets.

      1 reply 0 retweets 0 likes
    9. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      If rich countries can do with less, supply (of other vaccines) for poorer countries will be more. I didn't say there was an excess now because there's clearly a shortage now *everywhere*, and hence the painful discussions of trade-offs, but it's pretty straightforward.

      1 reply 0 retweets 0 likes
    10. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      Again, I think you're overly optimistic about liquidity in the vaccine market.

      1 reply 0 retweets 0 likes
      zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Not the way things are, you are right. But the way things are is pretty terrible. I'm pointing out that equity is not at all on one side of the trade-off debate. Ideally, yeah, we increase the supply of stable/easier one-dose vaccines and do away with the trade-off. Of course.

      12:31 PM - 2 Jan 2021
      • 1 Like
      • Alex Merz
      2 replies 0 retweets 1 like
        1. Alex Merz‏ @Merz 2 Jan 2021
          Replying to @zeynep @halvorz

          My real hope is that we end up with a priming jab followed by a nasal boost of a nanoparticle preparation. At present that's fantasy, but I'm optimistic.

          0 replies 0 retweets 1 like
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        2. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
          Replying to @zeynep @Merz @halvorz

          Also, even in the US, where we'll probably stick to the booster schedule (though do you know why three weeks instead of four to six except to have sped up the Pfizer trial?) there'll be many who miss booster we should collect data.

          1 reply 0 retweets 2 likes
        3. Alex Merz‏ @Merz 2 Jan 2021
          Replying to @zeynep @halvorz

          Absolutely.

          1 reply 0 retweets 0 likes
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