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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep

      This pushback is necessary because of armchair vaccinologists like Nate Silver.

      1 reply 0 retweets 3 likes
    2. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep

      Also worth noting: not many of the scientists pushing a single dose regimen have substantial and specific prior experience in human vaccine development. Even if they are virologists or immunologists.

      2 replies 1 retweet 4 likes
    3. halvorz ¯\_(ツ)_/¯‏ @halvorz 2 Jan 2021
      Replying to @Merz @zeynep

      I have only seen one scientist with actual vaccine development experience weigh in on this and they were on the side of delayed dosage

      2 replies 1 retweet 3 likes
    4. halvorz ¯\_(ツ)_/¯‏ @halvorz 2 Jan 2021
      Replying to @halvorz @Merz @zeynep

      halvorz ¯\_(ツ)_/¯ Retweeted halvorz ¯\_(ツ)_/¯

      I've been looking for more but so far it's been frustratingly sparsehttps://twitter.com/halvorz/status/1345180640359182337 …

      halvorz ¯\_(ツ)_/¯ added,

      halvorz ¯\_(ツ)_/¯ @halvorz
      would really like to see comment from other vaccine experts on this, dug through the replies and QTs and couldn't find anything https://twitter.com/sandyddouglas/status/1344949258483621888 …
      Show this thread
      1 reply 0 retweets 2 likes
    5. halvorz ¯\_(ツ)_/¯‏ @halvorz 2 Jan 2021
      Replying to @halvorz @Merz @zeynep

      coming to the conclusion that vaccinologists need to be More Online

      2 replies 0 retweets 5 likes
    6. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @halvorz @Merz

      Again, I cannot resolve the debate within that field (except to keep calling for data collection) but I disagree a bit with Alex. The people with deep/appropriate expertise calling for delaying the booster aren't that few. That said, very thoughtful/leading people also disagree.

      3 replies 0 retweets 3 likes
    7. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      There's a very significant sampling bias here.

      1 reply 0 retweets 2 likes
    8. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Well, if we had started a placebo/booster in November when the signal emerged, we'd be halfway to a better answer. I realize it's not easy, but given the stakes the best answers are speed up production (make the trade-off moot) and collect data (make the trade-off informed).

      1 reply 0 retweets 1 like
    9. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @zeynep @halvorz

      I don't think anyone thought that the mRNA vaccines would show the kind of protection that they have so far shown. The concern was always that the vaccines would show more marginal effectiveness and trial design was driven by concerns that they'd be underpowered.

      1 reply 0 retweets 3 likes
    10. Alex Merz‏ @Merz 2 Jan 2021
      Replying to @Merz @zeynep @halvorz

      And there's also the issue that participants were consented for the trials-as-conducted. A change in design as you suggest would have required that everyone be re-consented.

      1 reply 0 retweets 2 likes
      zeynep tufekci‏Verified account @zeynep 2 Jan 2021
      Replying to @Merz @halvorz

      Yeah, I realize we were surprised with mRNA-vax efficacy. I totally remember the April-June headlines and predictions. I realize why we did the trials the way we did. It's just that given the terrible price of the shortages, we should have adapted the trials as fast as possible.

      12:11 PM - 2 Jan 2021
      • 2 Likes
      • 👩🏻‍💻 Alex Merz
      1 reply 0 retweets 2 likes
        1. New conversation
        2. Alex Merz‏ @Merz 2 Jan 2021
          Replying to @zeynep @halvorz

          The doses are being manufactured considerably faster than they're being adminstered.

          2 replies 0 retweets 3 likes
        3. zeynep tufekci‏Verified account @zeynep 2 Jan 2021
          Replying to @Merz @halvorz

          We have even bigger screwups, sure. For the moment. Maybe we'll manage to get stuck here. But that's not relevant to the UK booster spacing issue, and also doesn't make the shortage problem, or the deep global inequity, go away.

          1 reply 0 retweets 1 like
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