There are literally billions of people not getting vaccinated at the moment. We do not need an inferiority trial to do this ethically. There are many many ways to do this.
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If an idea is baseless or has already been shown to be pointless sure no need to waste more resources on it. But if that’s not yet the case, I don’t see the point of negotiating ourselves down without even asking for trials? Trillions are being spent on all this.
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Totally agree - we need to keep fighting for the $$$ and investment in science infrastructure, especially for public health-focused studies and not just licensure studies. I only point out that if even $ were available, the staff for the trials are at the breaking point.
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If the resource being discussed is people with the necessary skills to handle large scale human trials, what exactly does "getting more" look like?
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The resources simply aren’t an issue. If we want to run the trials, we can. It’s an issue of will. In US, decision makers will not benefit from moving to a single dose. They’ll all be vaccinated. So we are witnessing a lack of will and breakdown of global responsibility.
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