Advocating the potential for a single dose of #SARSCoV2 vaccines @zeynep @michaelmina_lab https://www.nytimes.com/2020/12/18/opinion/coronavirus-vaccine-doses.html?action=click&module=Opinion&pgtype=Homepage …
The points for studying this are good but the public message to many for skipping the 2nd dose is troubling when we don't really know what protection that provides
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Analyzing those who miss their second dose after usual attempts to contact them (although by definition, this group may be hard to contact for a follow up study) is where observational epidemiology could shine.
@UNCpublichealth has a great pharmacoepi group: I’ll ask if plans -
Have you heard medical ethicists’ take on 1-dose trials among high-exposure people otherwise low on vaccine list, maybe young low-wage essential workers...? I see the benefits but, bc exposure risk is SO patterned by SES & race in US, I’d want lots of ethical analysis in planning
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