Cutting vaccine dosage in half right now is like spiking the football before you're in the endzone. We have clear data that a two-dose series from Pfizer's or Moderna's vaccines provide protection against COVID-19. That is a major accomplishment. No need to tinker.
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Replying to @Ryan_Mac_Phd @cclaytonr
@michaelmina_lab &@zeynep wrote an article in NYT advocating for a one-dose regimen. They favor doing a trial first, but I don't see the point. The risk is that the effect of a single dose might wane over a longer period of time—or fail to reduce infectiousness. By the time....2 replies 0 retweets 2 likes
Replying to @LongDesertTrain @Ryan_Mac_Phd and
Advocating for a trial! Not only do many immunologists (Mina is one) agree, it was one of the first questions asked by the FDA expert panel, it was raised by Moderna and Pfizer, too, and apparently they are looking into this as well.
7:56 AM - 19 Dec 2020
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