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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Dr. Angela Rasmussen‏Verified account @angie_rasmussen 18 Dec 2020

      Dr. Angela Rasmussen Retweeted Eric Topol

      I agree with Dr. @EricTopol. While we should prioritize looking at a single dose regimen as this piece suggests, I worry that the take-home message is that it's okay to skip the second dose or get a booster many months later. We don't know that.https://twitter.com/EricTopol/status/1339957304247033856 …

      Dr. Angela Rasmussen added,

      Eric TopolVerified account @EricTopol
      Advocating the potential for a single dose of #SARSCoV2 vaccines @zeynep @michaelmina_lab https://www.nytimes.com/2020/12/18/opinion/coronavirus-vaccine-doses.html?action=click&module=Opinion&pgtype=Homepage … The points for studying this are good but the public message to many for skipping the 2nd dose is troubling when we don't really know what protection that provides
      Show this thread
      25 replies 46 retweets 297 likes
    2. This Tweet is unavailable.
    3. Eric Topol‏Verified account @EricTopol 18 Dec 2020
      Replying to @michaelmina_lab @angie_rasmussen

      We're at odds because you are taking 2 large trials that were designed to test 2 doses and suggesting one dose might be fine w/o sufficient data. The point estimate of 52% has a lower 95% CI of <30%. After masks, aerosols, etc, the last thing the public needs is more confusion.

      7 replies 1 retweet 52 likes
    4. Eric Topol‏Verified account @EricTopol 18 Dec 2020
      Replying to @EricTopol @michaelmina_lab @angie_rasmussen

      The paternalism accusation won't work. I've worked very hard to work against that BS. What you are missing is that no one likes shots, no one wants to get a 2nd shot with more side effects. You're unwittingly supporting that convenient truth.

      2 replies 0 retweets 25 likes
    5. Michael Mina‏Verified account @michaelmina_lab 18 Dec 2020
      Replying to @EricTopol @angie_rasmussen

      I agree with this point. But I don’t see why we should not do the trials? Maybe our lines of communication are crossing incorrectly. I think we should do the trials. We should start today. Shouldn’t we?

      3 replies 0 retweets 16 likes
    6. TAGHIVscience‏ @TAGHIVscience 18 Dec 2020
      Replying to @michaelmina_lab @EricTopol @angie_rasmussen

      Was there are rationale for publishing in the New York Times rather than a scientific journal?

      3 replies 0 retweets 8 likes
    7. Richard M. Carpiano, PhD, MPH‏ @RMCarpiano 18 Dec 2020
      Replying to @TAGHIVscience @michaelmina_lab and

      That's the key point. This should have been in a sci journal commentary. Not everything is fit for NY Times--esp as the 1 shot theory has been getting attn by news and we are so early into just rolling out the authorized 2 shot protocol in an ecosystem where misinfo abounds.

      1 reply 0 retweets 11 likes
    8. Dr. Angela Rasmussen‏Verified account @angie_rasmussen 18 Dec 2020
      Replying to @RMCarpiano @TAGHIVscience and

      Agreed. Already people are reading this as an endorsement of a one-shot regimen rather than a proposal for a trial. This is astonishing since yesterday @zeynep was arguing that scientists are not doing a good enough job communicating nuance to the public.

      2 replies 1 retweet 18 likes
    9. zeynep tufekci‏Verified account @zeynep 18 Dec 2020
      Replying to @angie_rasmussen @RMCarpiano and

      The idea for the one shot regimen—without a trial!—is already being pushed by very prominent politicians with a lot of power. I think the piece is pretty clear why this needs a trial. Of course I’m all for discussion especially since it needs resources and proper implementation.

      2 replies 1 retweet 12 likes
    10. Richard M. Carpiano, PhD, MPH‏ @RMCarpiano 18 Dec 2020
      Replying to @zeynep @angie_rasmussen and

      Clarity abt RCT a moot pt. Again, doesn't justify a NYT op-ed vs. sci journal commentary for expert discussion you say you seek. Implies a "well the horse already left the barn" rationale. If powerful politicians pushing misinfo a concern, then addressing that shld've been focus.

      1 reply 0 retweets 7 likes
      zeynep tufekci‏Verified account @zeynep 18 Dec 2020
      Replying to @RMCarpiano @angie_rasmussen and

      There seems to be broad agreement—here at least—that a trial is warranted and a disagreement on: if this should be a public discussion and venue. On the first I don’t think we have a choice. We haven’t since the beginning. That’s been an ongoing contention of mine. +

      1:00 PM - 18 Dec 2020
      • 2 Likes
      • Michael Bishop 🇨🇦🇺🇸
      1 reply 0 retweets 2 likes
        1. New conversation
        2. zeynep tufekci‏Verified account @zeynep 18 Dec 2020
          Replying to @zeynep @RMCarpiano and

          On venue: Something like this needs attention and resources *and* public understanding—The fact I would argue exactly to prevent misinformation and misunderstanding. Doesn’t preclude other writing.

          2 replies 0 retweets 2 likes
        3. TAGHIVscience‏ @TAGHIVscience 18 Dec 2020
          Replying to @zeynep @RMCarpiano and

          "While we know that the single dose can protect against disease" seems like a strong statement - these were post hoc analyses, right? Your piece doesn't help any reader understand why post hoc analyses are problematic.

          0 replies 0 retweets 4 likes
        4. End of conversation

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