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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Steve Joffe‏ @SteveJoffe 18 Dec 2020

      1/ The hints that single doses of the Pfizer/BioNTech & Moderna vaccine are protective are really important, & I'm glad @zeynep & @michaelmina_lab call for studying them. The case for comparing 2 doses to 1 dose plus placebo is compelling. https://www.nytimes.com/2020/12/18/opinion/coronavirus-vaccine-doses.html …pic.twitter.com/k41BA7Npeg

      4 replies 8 retweets 41 likes
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    2. BiotechObserver‏ @BiotechObserver 18 Dec 2020
      Replying to @SteveJoffe @matthewherper and

      Do you folks pretend there was no phase 1 data, or did you just not bother to look at it? The reason for two doses is clear. By the time you test out a new dosing regimen, there will be ample supply of this and other vaccines

      1 reply 0 retweets 1 like
      zeynep tufekci‏Verified account @zeynep 18 Dec 2020
      Replying to @BiotechObserver @SteveJoffe and

      Of course we looked at phase I/II data and hence the suggestion for excluding 65+ folks from such a trial. (There will be some natural experiment data on that group, and we should look at that data, but we should not do that ourselves and we should encourage 65+ to get booster).

      5:51 AM - 18 Dec 2020
      • 1 Like
      • Walt Axson
      1 reply 0 retweets 1 like
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        2. Matthew Herper‏Verified account @matthewherper 18 Dec 2020
          Replying to @zeynep @BiotechObserver and

          Practically, would people enroll in a one dose trial for an authorized vaccine?

          3 replies 0 retweets 2 likes
        3. zeynep tufekci‏Verified account @zeynep 18 Dec 2020
          Replying to @matthewherper @BiotechObserver and

          There's a shortage, so you could enroll 1-Among those who'd never get one quickly now; 2-Call for volunteers with promise of monitoring and end-to-trial if a spike is observed. Given the data, both a rapid spike or severe disease are quite unlikely. Immunity isn't binary.

          1 reply 0 retweets 3 likes
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