Geeky question, is there an explanation for why the Moderna vaccine is stable longer than the Pfizer one in terms of cold storage requirements since they're both mRNA? Or is it just that Moderna tested for longer storage times and Pfizer didn't? Links to long papers welcome!
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Replying to @zeynep
As I understand it, Moderna developed a new lipid nanoparticle that was much stronger than the previous state of the art https://scholar.google.com/scholar?q=moderna+lipid+nanoparticles+covid&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&u=%23p%3DGuS3LLrmT7MJ …
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Replying to @drewconway
Right, I'm wondering why/if there isn't a way to license or apply this to Pfizer as well? The difference isn't marginal; will likely have huge impact on whether high-risk groups (outside of hospitals) can be vaccinated widely and quickly.
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Replying to @zeynep @drewconway
Pfizer is working in a new formulation that will allow storage at higher temperatures.https://www.fiercepharma.com/vaccines/amid-cold-chain-blues-pfizer-looks-to-powder-vaccine-formula-2021-report …
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