Geeky question, is there an explanation for why the Moderna vaccine is stable longer than the Pfizer one in terms of cold storage requirements since they're both mRNA? Or is it just that Moderna tested for longer storage times and Pfizer didn't? Links to long papers welcome!
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I’m so thrilled AstraZeneca blew it.
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I wouldn't say they've blown it. AstraZeneca came at the vaccine with the mindset that it needed to be cheap and available to the majority of the world's population. That's a little more difficult than tailoring to the rich countries who can afford it.
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I want to get the Dolly Parton-sponsored vax (Moderna) but since it's more temp-stable, will settle for Pfizer so it's available for rural/remote areas of the world.
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Your attention is invited to one example in the US:https://www.wtrf.com/belmont-county/belmont-county-health-dept-will-receive-their-shipment-of-covid-19-vaccine-next-week/ …
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Not even an accelerated stability study has been done on any of these vaccines. It’s just one big experiment.
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Honestly the Pfizer system has such a high fussiness factor I think they will need to do a v2 as fast as they can that permits error. I'm concerned about someone leaving a vial tray out too long tbh.
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I believe BioNtech is working on a tweek to the vaccine to make it require less frigid temperatures.
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In Canada, govt leaders agreed that the northern, remote areas wouldn't get the Pfizer vaccine at all and would wait for the Moderna vaccine.
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Ebola vaccine was kept at -80, so curious to know why there isn't a lesson to be taken there.
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I look forward to dipping dots partnership with pfizer for distribution
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